Translation Flashcards
(8 cards)
What is translation in the context of health interventions?
The process of turning observations in the laboratory, clinic, and community into interventions that improve the health of individuals and the public
Austin, 2021
Translation includes diagnostics, therapeutics, medical procedures, and behavioral changes.
What is a key characteristic of the translation process according to Austin?
It is a multistep, multidomain, multidiscipline recursive web that resembles a metabolic pathway map but produces a product that bears no resemblance to the starting material, and is rarely successfully produced.
What is translational science?
The study of translation itself, focusing on the scientific principles of the translational process.
What are the two main points of translation?
- Applying discoveries generated during research in the laboratory and in preclinical studies to the development of trials and studies in humans (Bench to Bedside)
- Enhancing the adoption of best practices (and policies) in the community
These loci represent the core focus areas in translational science.
What is an important aspect of translational science?
Cost-effectiveness of prevention and treatment strategies
This aspect ensures that strategies are not only effective but also economically viable.
What does ‘Bench to Bedside to Curbside (Broadway)’ refer to?
The process of moving from discovery to practice to policy
This phrase highlights the journey of scientific findings from the laboratory to real-world applications.
How is the process of translation characterized in reality?
It is not linear but iterative and can go in multiple directions
This indicates that translational science involves feedback loops and adaptations rather than a straightforward path.
Fill in the blank: The process of moving from discovery to development to delivery is part of _______.
[translational science]
This emphasizes the comprehensive nature of translational science in applying research findings.
