Transport Accross Cell Membranes Flashcards

(50 cards)

1
Q

What model describes the arrangement of the cell membrane components?

A

Fluid-mosaic model

The fluid-mosaic model describes the cell membrane’s structure, consisting of a bi-layer of phospholipids with proteins integrated throughout.

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2
Q

What does ‘fluid’ refer to in the fluid-mosaic model?

A

Phospholipids are constantly moving

The term ‘fluid’ indicates the dynamic nature of the phospholipid bilayer.

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3
Q

What does ‘mosaic’ refer to in the fluid-mosaic model?

A

Proteins scattered through the bilayer

‘Mosaic’ refers to the arrangement of proteins embedded in the phospholipid bilayer, akin to tiles in a mosaic.

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4
Q

What is a glycoprotein?

A

Protein with carbohydrate attached

Glycoproteins play key roles in cell recognition and signaling.

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5
Q

What is a glycolipid?

A

Lipid with carbohydrate attached

Glycolipids contribute to the stability and recognition functions of the cell membrane.

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6
Q

What is the primary function of the phospholipid bilayer?

A

Form a barrier to dissolved substances

The hydrophobic center of the bilayer prevents water-soluble substances from passing through.

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7
Q

What types of molecules can diffuse through the phospholipid bilayer?

A

Small, non-polar molecules like CO2

The bilayer allows certain small, non-polar molecules to diffuse freely, while larger or polar molecules require specific transport mechanisms.

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8
Q

How do channel proteins and carrier proteins function?

A

Allow large molecules, polar molecules, and ions to pass through the membrane

These proteins facilitate the transport of substances that cannot easily pass through the lipid bilayer.

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9
Q

Can water diffuse through the cell membrane?

A

Yes, through osmosis due to its small size

Despite being polar, water can pass through the membrane efficiently because of its small molecular size.

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10
Q

What role do proteins with carbohydrates attached play in cells?

A

Act as antigens for cellular recognition

These proteins are crucial for the immune response and help in cell signaling and adhesion.

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11
Q

What is the function of cholesterol in the cell membrane?

A

Restricts movement of molecules and provides stability

Cholesterol fits between phospholipids, reducing membrane fluidity and helping maintain its integrity.

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12
Q

What is the role of intrinsic proteins in the cell membrane?

A

Facilitate active transport or facilitated diffusion

Intrinsic proteins span the membrane and assist in the movement of substances across it.

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13
Q

What effect does insulin have on liver cells?

A

Tells the cell to start absorbing glucose

Insulin binds to receptor proteins, triggering glucose uptake, which is vital for regulating blood sugar levels.

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14
Q

What is the importance of cell adhesion in tissues?

A

Allows cells to connect to one another

Cell adhesion is crucial for forming tissues and maintaining structural integrity in multicellular organisms.

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15
Q

True or False: Animal cells maintain their shape through cell walls.

A

False

Animal cells maintain shape through their cytoskeleton and membrane structure, not through cell walls.

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16
Q

What is the role of cytoskeletal filaments in animal cells?

A

Helps maintain cell shape

Cytoskeletal filaments provide structural support, especially in cells that lack rigid cell walls.

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17
Q

What effect do non-polar solvents (e.g., alcohol or acetone) have on cell membranes?

A

Non-polar solvents disrupt the cell membrane by inserting themselves into the bilayer and forming hydrogen bonds with phospholipids, increasing permeability

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18
Q

How does alcohol increase membrane permeability?

A

Alcohol disrupts the membrane structure by forming hydrogen bonds with phospholipids and breaking bonds in proteins, destabilizing the bilayer.

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19
Q

What happens to cell membranes when exposed to high temperatures?

A

High temperatures increase membrane fluidity, causing the membrane to become more permeable and allowing pigments to leak out.

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20
Q

What role does a colorimeter play in studying membrane permeability?

A

A colorimeter measures the amount of pigment that leaks out of cells by analyzing the absorbance of light in the solution.

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21
Q

Why are pigments like betalains used to study membrane permeability?

A

Betalains are contained in the vacuole of beetroot cells and leak out when the membrane is damaged, allowing for quantifiable analysis of permeability

22
Q

How does a colorimeter determine the concentration of pigments in a solution?

A

It passes light through the solution and measures how much light is absorbed, using a filter to select the wavelength opposite to the color of the pigment.

23
Q

Why is a calibration curve important when using a colorimeter?

A

A calibration curve allows the comparison of unknown sample absorbance values to known concentrations to determine the pigment concentration.

24
Q

What is simple diffusion?

A

Simple diffusion is the passive movement of molecules or ions from an area of high concentration to an area of low concentration until equilibrium is reached

25
What type of molecules can diffuse through a membrane via simple diffusion?
Small, non-polar molecules like oxygen and carbon dioxide.
26
How does the concentration gradient affect simple diffusion?
A greater concentration difference increases the rate of diffusion.
27
How does membrane thickness affect diffusion?
Thinner membranes reduce the distance particles need to travel, increasing diffusion rates.
28
How does surface area affect diffusion?
A larger surface area allows more particles to diffuse at the same time, increasing the rate of diffusion
29
How does temperature affect diffusion?
Higher temperatures increase the kinetic energy of particles, leading to faster diffusion.
30
What is facilitated diffusion?
A passive process where larger or charged particles (e.g., ions, glucose) move down their concentration gradient through carrier or channel proteins in the membrane
31
How do carrier proteins work in facilitated diffusion?
Specific molecules bind to the protein, causing it to change shape and allow the molecule to pass through the membrane
32
How do channel proteins function in facilitated diffusion?
They form pores in the membrane, allowing specific molecules or ions to pass through.
33
What is Fick’s Law?
The rate of diffusion is proportional to the surface area × concentration difference divided by the thickness of the exchange surface.
34
What is the role of carrier proteins in facilitated diffusion?
Carrier proteins bind to large molecules, change shape, and release the molecule on the other side of the membrane.
35
What is the role of channel proteins in facilitated diffusion?
Channel proteins form water-filled, hydrophilic channels that allow specific charged particles or ions to diffuse across the membrane.
36
How does the concentration gradient affect the rate of facilitated diffusion?
A greater concentration difference increases the rate of facilitated diffusion until equilibrium is reached or all proteins are in use.
37
How does the number of channel or carrier proteins affect the rate of facilitated diffusion?
A greater number of proteins increases the rate of diffusion, but once all proteins are in use, the rate cannot increase further, making it a limiting factor.
38
What happens when all channel and carrier proteins are in use during facilitated diffusion?
The rate of diffusion levels off and cannot increase further, even with a higher concentration gradient
39
How do protein channels differ from carrier proteins in facilitated diffusion?
Protein channels act as simple “tunnels” for charged particles, while carrier proteins change shape to transport specific molecules.
40
How is the dilution factor (DF) calculated?
DF = vi (initial volume) divided by vf (final volume)
41
Active transport
The movement of molecules across a cell membrane from a region of lower concentration to a region of higher concentration requires ATP
42
How does active transport differ from passive transport?
Active transport requires energy (ATP) and moves substances against their concentration gradient, while passive transport does not require energy and moves substances down their concentration gradient.
43
What is the role of carrier proteins in active transport?
Carrier proteins bind to specific molecules and use energy (ATP) to change shape, allowing the molecules to be transported across the membrane against their concentration gradient
44
Give an example of a process that uses active transport
The sodium-potassium pump (Na+/K+ pump) is an example, where sodium ions are pumped out of a cell and potassium ions are pumped into the cell, both against their concentration gradients
45
Why is ATP required for active transport
ATP provides the necessary energy for carrier proteins to change shape and move molecules or ions against their concentration gradients.
46
What is bulk transport (vesicular transport)?
Bulk transport is a type of active transport in which large quantities of materials, such as macromolecules or particles, are transported into or out of the cell in vesicles.
47
What are the two main types of bulk transport?
Endocytosis (taking substances into the cell) and exocytosis (expelling substances from the cell).
48
What is the difference between primary and secondary active transport
Primary active transport directly uses ATP to transport molecules, while secondary active transport uses the energy created by primary active transport (like a sodium gradient) to move other molecules
49
What is the sodium-potassium pump, and why is it important?
The sodium-potassium pump transports sodium ions out of the cell and potassium ions into the cell, crucial for maintaining cellular function, resting membrane potential, and osmotic balance.
50
What is co-transport in active transport
Co-transport involves the simultaneous transport of two different substances across a membrane, one moving down its concentration gradient (providing energy) and the other moving against its gradient