Transport Across Cell Membranes Flashcards
(17 cards)
What are the functions of proteins in the membrane?
- Structural support
- Channels to transport water-soluble substances
- Allow active transport through carrier proteins
- Cell-surface receptors for identifying cells
What are the functions of cholesterol in the membrane?
- Reduce lateral ( sideways ) movement of other molecules
- Make the membrane less fluid at high temperatures
- Prevent leakage of water and dissolved ions from the cell
How does cholesterol reduce movement of the phospholipids in the membrane?
By pulling together their fatty acid tails
What are the functions of glycolipids in the membrane?
- Act as recognition sites
- Help maintain stability
- Help cells attach to each other to form tissues
What are extrinsic proteins?
Proteins on the surface of the cell-membrane
What are intrinsic proteins?
Proteins that are embedded within the cell membrane
What are the functions of glycoproteins in the membrane?
- Act as receptors and neurotransmitters
- Help cells attach to each other and form tissues
- Allows cells to recognise each other
Why can some molecules not freely pass through the membrane?
- They are not soluble in lipids
- They are too large
- They are the same charge as the protein channels and so repel
- They are polar so cannot pass through the non-polar hydrophobic tails
What does the fluid mosaic model mean?
- Fluid because the phospholipids can move which gives the membrane flexibility
- Mosaic because the proteins that are embedded within the membrane vary in shape, size, and pattern
What is diffusion?
The net movement of non-polar molecules from an area of high concentration to an area of low concentration until they are evenly distributed
What are the two proteins involved in facilitated diffusion?
- Protein channels
- Carrier proteins
How do protein channels work?
- Allow polar molecules, charged and water soluble molecules to pass through
- They bind to the protein which causes it to change shape so that it closes on one side of the membrane and opens it on the other side
How do carrier proteins work?
- Molecule that is specific to the protein binds to it
- Causes a change in shape where the molecule is released inside of the membrane
What is osmosis?
Movement of water molecules from an area of high water potential to an area of low water potential through a partially permeable membrane
How does co-transport of work in the ileum?
- Sodium ions are pumped out of the epithelial cell into the blood by active transport
- This creates a diffusion gradient
- Ions move into the epithelial cell by facilitated diffusion, carrying glucose and amino acids with it
- The glucose and amino acids then diffuse from high concentration in the epithelial cell to the low concentration in the blood
What increases the rate of gas exchange by diffusion ?
- Increase in surface area
- Decrease in diffusion distance
- Steeper diffusion gradient
- Increase in temperature
What is water potential?
- Pressure caused by water molecules
- The addition of a solute to pure water will lower its water potential