Trauma Flashcards
(94 cards)
What are the causes of dilated neck veins in a trauma patient?
Tension pneumothorax
Tamponade
Myocardial contusion (cardiogenic)
MI (cardiogenic)
Air embolism
What is the cardiac box
Nipples
Clavicles
Costal cartilages.
What are the indications to activate the MTP?
- Replacement of 50% of blood volume within 1 hour.
- Replacement of 100% of blood volume within 24 hours.
- Haemorrhagic shock with active bleeding
- Use of 4 units of RBC within 4 hours.
- Physician concern
- Majorly injured patient with high likelihood of transfusion requirement.
ATMIST - what does it stand for
Age
Time of incident
Mechanism of injury
Injuries sustained.
Signs and symptoms.
Treatment.
What does AMPLE stand for
Allergies
Meds
PMHx or pregnant
Last meal
Environment - patients family, responders
What is damage control and what are the principles?
A deliberate and pre-emptive set of non-traditional maneuvers used to reverse the pre-terminal effect of exsanguination, massive injury and shock
Goal is to temporize management of major injuries with directed resuscitation and staged surgery, to allow for the resuscitation and restoration of normal physiology
Why is temporary abdominal closure used?
Prevent heat and moisture loss and protect the abdominal viscera
Reduce the risk of abdominal compartment syndrome in a patient that is likely to have received a large amount of IVF resuscitation and undergo tissue interstitial oedema
Difficulty or inability to close the abdomen due to point B
Damage control surgery has taken place and a relook procedure is required
Stapled off bowel ends
Packs in place for haemorrhage control
Vascular shunts created for named vessels requiring definitive repair
Explain the pathophysiology of trauma
Ebb and Flow
Ebb
Short duration of severe shock and reduction in enzyme activity and O2 consumption
Hypovolaemia leads to decreased tissue perfusion causing release of catecholamines
Ebb is treated by good resuscitation
Flow (2 parts)
Hormonal mediators such as sympathetic system, cortisol, ADH and aldosterone leads to increased fluid conservation via sodium retention
Hyperdynamic state stimulated by inflammation
Catabolic phase - Fat/protein mobilization and weight loss
- Increased urine nitrogen excretion
Anabolic phase - Fat/protein store restoration and weight gain
- Normal/high - BGL, glucose production, FFA, insulin, catecholamines
- High - glucagon, O2 consumption, CO, temperature
Normal lactate
What is the definition of shock
Inadequate delivery of oxygenated blood to the tissues causing cellular hypoxia
Initially leading to reversible ischaemic injury then irreversible damage
What factors are used to grade hypovolaemic shock
Heart rate
Blood pressure
Pulse pressure
Respiratory rate
At what temperature and pH does the coagulation cascade stop working?
pH < 7.2
Temperatures < 34
What does FFP contain?
Volume 250mls
All clotting factors
Natural pro and anticoagulants (protein C and S, anti-thrombin and tissue factor pathway inhibitor)
Fibrinogen 800mg
Albumin
What does cryoprecipitate contain?
Volume 20mls
Fibrinogen
vWF/Factor VIII complex
Factor VIII
Benefit - rich source of fibrinogen in 1/8 of the volume.
How does tranexamic acid work?
TXA binds to plasminogen inactivating it
- prevents it being converted to plasmin
- plasmin breaks down fibrin
- thus assists with clot stabilisation
What are the risks of transfusion?
Hyperkalaemia
Infection
- HIV, CMV, EBV
Haemolytic transfusion reactions
- very rare with ABO compatability testing.
Immunomodulation in transplant patients
Graft versus host disease
How does TEG and ROTEM work?
○ Blood sample in cup with pin which oscillates creating fibrin strands.
○ For TEG the cup oscillates whereas for ROTEM the pin oscillates.
○ TEG uses a mechanical sensor whereas ROTEM uses and optical sensor.
○ In both tests a “clot activator” is given to stimulate the clot.
They are thus very similar tests - evaluating the formation of a clot around a pin.
Explain the TEG graph
R time
- Measures time for the blood to begin clotting after the addition of a clotting activator.
- Measures the beginning of fibrin formation.
- Prolonged in clotting factor deficiencies - thus treated with FFP
K time
- Kinetical phase
- Measures time it taken for the clot to reach a certain level of firmness (amplitude of 20mm)
- Measures fibrinogen level - treated with cryoprecipitate.
Alpha angle
- Slope between R and K
- Reflects rate at which fibrin cross linking occurs. Normally 50-70 degrees
- Represents fibrinogen
- Angle is decreased in low fibrinogen levels - treated with cryoprecipitate.
TMA - time to maximum amplitude
- Measures strength and firmness of the blood clot.
- Represents platelets (80%) and fibrin (20%)
- If MA is decreased - thrombocytopenia or reduced platelet function
- Treat with platelets or desmopressin.
AY30
- Measures clot lysis at 30 minutes
- Measure of fibrinolysis/plasminogen activation
Treated with tranexamic acid.
What is the definition of the massive transfusion protocol?
Definition
- administration of 100% of blood volume within 4 hours.
- administration of 50% of blood volume within 1 hour.
What are the end points for the MTP?
Active surgical bleeding has been controlled
Temp < 35
pH > 7.3
Fibrinogen > 1.5
INR < 1.5
Hb > 80
When assessing a limb trauma - what are hard signs of vascular compromise?
Pulselessness
active bleeding
Expanding haematoma.
Thrill or bruit.
Unilateral cool and pale periphery.
What dose the mangled limb severity score look at?
Score > 7 predicts high liklihood of needing an amputation
Skeletal/soft tissue injury
- low energy
- medium energy
- high energy
- very high energy
Limb ischaemia
- pulse reduced but perfusion normal
- no pules, perfusion cold
- insensate
Shock
- SBP > 90
- SBP transiently < 90
- SBP < 90
Age
- <30
- 30-50
- 50+
What are risk factors for a wound infection in an extremity?
Severity of injury
Delay from injury to surgical care (> 6hrs)
Failure to use prophylactic abx
Inappropriate wound toilet
Lack of coverage of bony structures
Inappropriate wound closure (e.g. primary closure in contaminated/contused wounds)
Open fracture wounds that are more likely to get infected
What is the pathophysiology of compartment syndrome?
- Is an increase in the hydrostatic pressure within an enclosed oesteofascial space causing decreased perfusion of muscles and nerves within a compartment.
- The pressure within the compartment increases until the intramuscular arteriolar pressures are exceeded
- Means blood is not entering capillaries.
- Cascade of events
○ Initially local trauma leading to bleeding and oedema - results in increased interstitial pressure
○ Vascular occlusion and subsequent myoneural ischaemia develops. - Leads to muscle ischaemia.
What are the landmarks for a lower limb fasciotomy - and what nerves do you need to avoid on both sides
Lateral
- 2cm below fibula head
- lateral malleolus.
- avoid common peroneal nerve and superficial peroneal nerve at distal aspect of the wound
Medial
- 2cm below tibial tuberosity
- 2cm above medial malleolus
- avoid the GSV and saphenous nerve