Treatment

Question 1

Neisseria meningitides

Answer 1

Ceftriaxone
Cell wall synthesis inhibitor

Question 2

E Coli

Answer 2

Trimethoprim
Inhibitor of folic acid synthesis

Question 3

Staph aureus

Answer 3

Cellulitis - flucloxacillin
MRSA - vancomycin
Both cell wall inhibitors

Question 4

Staph epidermis

Answer 4

Cellulitis - flucloxacillin
Cell wall synthesis inhibitor

Question 5

Strep pyogenes

Answer 5

Flucloxacillin
Vancomycin if allergic to penicillin

Question 6

C. difficile

Answer 6

Enteral Vancomycin or IV metronidazole (if enteral is unavailable)

Question 7

Strep pneumonia

Answer 7

Mild - amoxicillin
Moderate - amoxicillin and doxycycline
Severe - cephalosporin and doxycycline
All cell wall synthesis inhibitors

Question 8

Viridans streptococci

Answer 8

Surgical antibiotic prophylaxis

Question 9

Haemophilia influenzae

Answer 9

Amoxicillin
Co-amoxiclav

Question 10

Salmonella typhi

Answer 10

Ceftriaxone

Question 11

Legionella pneumophila

Answer 11

Clarythromycin

Question 12

Epstein Barr virus

Answer 12

Acyclovir

Question 13

Varicella zoster

Answer 13

Acyclovir
Viral replication inhibitor

Question 14

Hepatitis B

Answer 14

No cure - supportive treatment

Question 15

Hepatitis C

Answer 15

Ribovarin and interferon

Question 16

HIV

Answer 16

HAART

Question 17

Adenovirus

Answer 17

Supportive treatment

Question 18

Norovirus

Answer 18

Supportive treatment
(anti-pyretics, IV fluids)

Question 19

Plasmodium falciparum

Answer 19

Quinine
Doxycycline

Question 20

Candida albicans

Answer 20

Nystatin
Clotrimazole

Systemic: amphotericin B

Question 21

Cellulitis

Answer 21

Flucloxacillin
Effective against both staph aureus and strep pyogenes
Beta lactam
Penicillin
Cell wall inhibitor

Question 22

Tonsillitis

Answer 22

Penicillin V

Question 23

Sepsis

Answer 23

Ceftriaxone
Sepsis six:
- senior help
- give o2 if below 92%
- send blood tests including culture
(eg ALT and AST tests, renal dysfunction tests, FBC, CRP, blood has to check lactate etc.)
- give IV antibiotics and consider source control (removal or drainage of source of infection)
- consider IV fluids
- monitor (urine output, observations)

Question 24

Peritonitis

Answer 24

E. Coli, therefore trimethoprim

Question 25

Skin abscess

Answer 25

Staph aureus, therefore flucloxacillin (cellulitis) or vancomycin (MRSA)

Question 26

Pneumonia

Answer 26

Haemophilus influenzae, therefore Co-amoxiclav

Question 27

Pneumonia + sepsis

Answer 27

Streptococcus pneumoniae, therefore: Mild pneumonia: Amoxicillin (Doxycycline if penicillin allergy) Moderate: Amoxicillin AND Doxycycline (Doxycycline onlv if penicillin allergy) Severe: Co-amoxiclav and Doxycycline (cephalosporin and Doxycycline if penicillin allergy) Cell wall synthesis inhibitors

Question 28

Profuse diarrhoea

Answer 28

Clostridium difficile, so vancomycin

Question 29

Aortic valve stenosis/endocarditis

Answer 29

Penicillin or gentamicin

Question 30

Pharyngitis

Answer 30

Adenovirus or EBV - supportive Streptococcus pyogenes - flucloxacillin

Question 31

Shingles

Answer 31

Varicella zoster - acyclovir

Question 32

Malaria

Answer 32

Plasmodium falciparum- quinine

Question 33

Schistosomiasis

Answer 33

Helminths - praziquantel

Question 34

Pneumocystis jirovecii

Answer 34

Co-trimoxazole