TREATMENT Flashcards

(7 cards)

1
Q

What are the treatments for MM?

A
  • chemotherapy
  • steroids
  • anti myeloma drugs
  • stem cell transplant in some dases
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2
Q

Why are corticosteroids used?

A

Controls inflammation caused by myeloma cells and stops WBC from going to swollen areas of body

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3
Q

How does thalidomide treat MM?

A

Causes the degradation of two transcription factors which are needed for growth and function

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4
Q

How does lenalidomide treat MM?

A

Vascular endothelial growth of myeloma cells is inhibited so blood vessels cannot form

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5
Q

How does daratumubab treat MM?

A

Attaches to the CD38 protein and activates immune system to kill them

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6
Q

How does bortezomib treat MM?

A

blocks proteosomes from breaking down proteins so the cell eventually dies

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7
Q

Why is a stem cell transplant done?

A

high dose chemo kills stem cells, so a transplant replaces the healthy ones destroyed by chemo

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