Treg Flashcards
(3 cards)
1
Q
n Treg
A
Generated in the thymus, CD4+ Foxp3+ Cd25+
2
Q
iTreg - TGFb
A
Induced Treg that occurs when Naive T cells are activated in the presence of TGFb in the presence or absence of Retinoic acid and IL-2.
Express Foxp3 and secrete mainly TGFb
3
Q
iTreg - IL-10
A
IL-10 tregs remain foxp3 negative after conversion and are defined by abundant IL-10 secretion
