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Treg Flashcards

(3 cards)

1
Q

n Treg

A

Generated in the thymus, CD4+ Foxp3+ Cd25+

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2
Q

iTreg - TGFb

A

Induced Treg that occurs when Naive T cells are activated in the presence of TGFb in the presence or absence of Retinoic acid and IL-2.
Express Foxp3 and secrete mainly TGFb

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3
Q

iTreg - IL-10

A

IL-10 tregs remain foxp3 negative after conversion and are defined by abundant IL-10 secretion

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