Truncal Blocks (week 6) Flashcards
What are the absolute contraindications to regional anesthesia?
- patient refusal
- uncorrected coagulation deficiencies
- infection at the block site
Nagelhout, pg. 1141
In addition to potentially spreading or seeding the infection, why else should regional anesthesia not be performed when there is an active infection at the site?
- acidic environment will reduce effectiveness of the block
Nagelhout, pg. 1141
Allergies to which class of local anesthetic are more common?
- Ester
ONE EYED ESTER IS A NASTAY BITCH
Nagelhout, pg. 1141
What is the double crush phenomenon as it relates to regional anesthesia?
- The theory that patients with preexisting neurologic disease may experience permanent injury following a second insult
Nagelhout, pg. 1141, 1143
Why are allergies to ester local anesthetics more common?
- The metabolite paraaminobenzoic acid (PABA) is a known allergen
Nagelhout, pg. 1141
Name the truncal blocks that can be utilized for surgeries in the chest/thorax area
- PECS I/II
- Paravertebral
- Intercostal
- Erector spinae
Nagelhout, pg. 1142 - Fig. 50.1
Name the truncal blocks that be utilized for surgeries in the abdominal/back areas
- Transversus Abdominis
- Quadratus Lumborum
- Erector Spinae
Nagelhout, pg. 1142 - Fig. 50.1
Documented complications associated with regional anesthesia include:
* _________
* ________
* _________
* __________
* _________
- direct/indirect nerve injury
- local anesthetic systemic toxicity (LAST) events
- vascular injury
- hematoma
- infection
Nagelhout, pg. 1142
While the overall incidence of severe or permanent peripheral nerve injury (PNI) following a block is extremely low, it is not uncommon in the early postoperative period for as many as 15% of patients to complain of _____________
- paresthesia
aka postoperative neurologic symptoms (PONS)
Nagelhout, pg. 1142
True or false:
The lack of motor response when using a peripheral nerve stimulator is the best way to guarantee that intraneural needle placement has not occured, thus avoiding direct nerve injury
- False - lack of motor response does NOT guarantee that intraneural needle placement has not occured
Nagelhout, pg. 1142
True or false:
All local anesthetics used in clinically relevant concentrations are potentially neurotoxic
- True story
Nagelhout, pg. 1141
Indirect nerve injury refers to nerve injury occuring from local anesthetic toxicity, ____________, or _____________
- ischemia
- inflammation
Nagelhout, pg. 1142
All patients receiving peripheral blocks should have ____________, and blocks should be performed only in areas where ________________ are immediately available
- functional IVs
- patient monitoring, equipment, and drugs to treat LAST
Nagelhout, pg. 1143
Selection of local anesthetic is dependent on what 3 things?
- onset
- duration
- desired density (pain management vs primary anesthetic)
Nagelhout, pg. 1143
In general, the highest concentrations of local anesthetic in the blood are found after _____________ blockade
- intercostal
Nagelhout, pg. 1143
The type of local anesthesia may have a role in the development of neurotoxicity, with _________ being more toxic than ___________
- esters
- amides
Degree of neurotoxicity is dose dependent
Nagelhout, pg. 1143
How long does Exparel provide pain relief?
Up to 72 hrs
Nagelhout 7th, Ch. 50, pg. 1143
What is the maximum dose of Exparel?
266mg
Nagelhout 7th, Ch. 50, pg. 1143
What is the unique characteristic of Exparel that allows for such a long duration of action?
- DepoFoam
basically an extended release “capsule”
Nagelhout, pg. 1143
Because of its delayed onset, it is not uncommon to mix Exparel with _________ to reduce the onset effect time of the block
- standard bupivacaine
Nagelhout, pg. 1143
Exparel should not be adminstered for at least ___________ following any injection of lidocaine
- 20 minutes
Nagelhout, pg. 1143
Other formulations of bupivacaine should not be given for at least ___________ after a procedure using Exparel
- 96 hours
Nagelhout, pg. 1143
Why is it essential for a topical antiseptic to dry before an injection of Exparel?
- antiseptic solutions may cause the liposomes to degrade, releasing toxic amounts of the drug into the plasma
Nagelhout, pg. 1143
Following a peripheral nerve block, patients should be observed for at least _________ for potential signs of LAST or other adverse outcomes as blood levels peak
- 30 minutes
Nagelhout, pg. 1144