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Neurology > Tuberculosis Meningitis > Flashcards

Tuberculosis Meningitis Flashcards

1
Q

Is it acute or chronic

A

Chronic

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2
Q

Causitive organism

A

Mycobacterium tuberculosis
Mycobacterium bovis

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3
Q

Meningitis from primary pulmonary tuberculosis is by

A

Bacteraemia

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4
Q

Metastatic foci after bacteraemia is

A

Meninges
Cerebral or spinal tissue
Choroid plexus

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5
Q

The infection (M.tuberculosis) spreads from the metastaic foci by _______ into _______________

A

Rupture into subarachnoid space

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6
Q

Reactivation of metastatic foci occurs

A

Spontaneous or by
Impaired immunity

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7
Q

Immunity impairment can be cause by

A

Measles infection
Alcohol use
Steroid use
AIDS etc

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8
Q

Clinical features of TB meningitis is caused by

A

Infection
Exudation
Vasculitis

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9
Q

Hydrocephalus in TB meningitis is due to

A

Obstruction of basal cisterns by exudation

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10
Q

Infarction in brain after tb meningitis is caused due to

A

Vasculitis

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11
Q

Clinical features stages in TB meningitis

A

Stage 1(early)
Stage 2(intermediate)
Stage 3(advanced)

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12
Q

Stage 1 clinical features

A

Non specific symptoms :
Fever
Lethargy

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13
Q

Stage 2 clinical features

A

Confusion
Cranial nerve paresis
Meningism
Vasculitis

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14
Q

Stage 3 clinical features

A

Coma

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15
Q

Why is staging important in TB meningitis

A

To predict the outcome of

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16
Q

Will there be seizures in Tb meningitis

A

Yes maybe

17
Q

Atypical tb meningitis presentation

A

Dementia (slow progressing)
Or fast like pyogenic meningitis

18
Q

Diagnosis

A

Lymphocytosis
Anaemia
PCR
Tuberculin skin test
Chest x ray
Ct scan and mri

19
Q

Will there be change in ADH secretion in TB meningitis

A

ADH secretion will be reduced due to hypothalamus damage or infarction

20
Q

Treatment

A

Isoniazid
Rifampicin
Pyrazinamide

21
Q

In drug resistance tb meningitis we give

A

Streptomycin
Or
Ethambutol

22
Q

Drugs that penetrate meninges well are

A

Isoniazid and
Pyrazinamide

Neurology (5 decks)

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