Flashcards in Tumor dedifferentiation/differentiation or redifferentiation Deck (4)
What is cellular plasticity?
dramatic shift in cellular phenotype
Why is cellular plasticity important in cancer biology?
Because it contributes to the progression of the tumor, to metastatic potential and to resistance to therapeutic interventions
What is tumor cell dedifferentiation?
When a tumor cell loses it's specialized properties and takes on a less differentiated phenotype