Tumor markers

Question 1

PSA (prostate specific antigen)

Answer 1

BPH

Prostate carcinoma

Question 2

Prostatic acid phosphatase

Answer 2

Prostate carincoma

Question 3

CEA (carcinoembryonic antigen)

Answer 3

Colorectal cancer
Pancreatic cancer
gastric, breast, thyroid medullary carincomas

Question 4

AFP (alpha-fetoprotein)

Answer 4

Neural tube defect, anencephaly
Hepatocellular carcinoma
Nonseminomatous germ cell tumor of testes (yolk-sac tumor)

Question 5

Beta-hcG

Answer 5

Hydatidiform moles
Choriocarcinomas
Gestational trophoblastic tumors

Question 6

CA-125

Answer 6

Ovarian, malignant epithelial tumors

Question 7

S-100

Answer 7

Melanoma
Neural tumors
Astrocytomas

Question 8

Alkaline phosphatase

Answer 8

Metastases to bone
Obstructive biliary disease
Paget’s disease of bone

Question 9

Bombesin

Answer 9

Neuroblastoma

Lung and gastric cancer

Question 10

TRAP (Tartate-resistant acid phosphatase)

Answer 10

Hairy cell leukemia

Question 11

CA-19-9

Answer 11

Pancreatic adenocarcinoma

Question 12

Calcitonin

Answer 12

Thyroid medullary carcinoma (C cells aka Parafollicular cells