Twin Studies Flashcards

1
Q

Fraternal twins (dizygotic DZ)

A

product of two different sperm and egg during the same pregnancy

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2
Q

Identical twins (monozygotic MZ)

A

product of the same sperm and egg during the same pregnancy

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3
Q

when can twins said to be concordant

A

if they both develop the condition of interest

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4
Q

what do twin studies have an enriched understanding of

A

contribution of genetic and environmental factors in human behaviour

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5
Q

concordance rate

A

the extent to which both twins share the same characteristic

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6
Q

issues with generalisability in twin studies

A

may not generalise to the broader population - twins are not necessarily representative of all individuals

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7
Q

what is a problem with twin studies often using volunteer sampling

A

biased sample - volunteers may all share similar characteristics

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8
Q

why are twin studies useful

A

no other human shares 100% of their concordance rate

no other way to study genetic influences so early

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9
Q

Application of twin studies to real life

A

help to identify trends in families

e.g. the Bloomburg family who couldn’t stay awake in the evenings

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10
Q

validity issues with twin studies

A

role of genes may be over emphasised

the reason for higher concordance rates in MZ over DZ twins may be environmental instead of due to genes

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11
Q

why can twin studies be seen as unethical

A

separated twin studies useful for looking at environmental and genetic factors - unethical as twins are now adopted together

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12
Q

high validity

A

natural control over environmental factors as twins usually share the same environment - we can be sure that differences in concordance rates are unlikely to be from environmental effects

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13
Q

Gottesman and Shields (1966) - sample

A

57 twin pairs found from 45,000 psychiatric patients where at least one had a schizophrenia diagnosis

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14
Q

Gottesman and Shields (1966) - findings

A

where one MZ twin had schizophrenia, co-twin at least 42 times more likely to have it than a person from the general population

same sex DZ twin at least 9 times more likely to have it if co-twin was diagnosed

in severe cases of Schizophrenia, concordance rate for MZ twins between 75-91 percent - strongly suggests some genetic basis for schizophrenia

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