Two Compartment Models

Question 1

Draw the two compartment model for IV bolus. What is each compartment and derive a formula?

Answer 1

Question 2

What is the equation of an IV bolus injection?

Answer 2

Question 3

How can one calculate A

Answer 3

Question 4

How can one calculate B

Answer 4

Question 5

Which is greater alpha or beta?

Answer 5

alpha > Beta

Question 6

What is the equation for the log linear line of IV bolus?

Answer 6

Question 7

How can one calculate half-life of beta?

Answer 7

Question 8

How can one calculate the feathered line?

Answer 8

Question 9

How can one calculate half-life of alpha?

Answer 9

Question 10

CP0 of IV bolus

Answer 10

Question 11

What is the equation for the volume of the central compartment?

Answer 11

Question 12

What is the equation of the volume of the distribution phase?

Answer 12

Question 13

How can one calculate the AUC of IV bolus dose?

Answer 13

mgL^-1H

Question 14

Clearance of IV bolus dose

Answer 14

Question 15

Fraction excreted unchange IV bolus dose

Answer 15

Question 16

Draw the diagram of oral adminsitration two compartment and its derived equation

Answer 16

Question 17

Oral Two compartment Dose Equation

Answer 17

Question 18

AUC Oral 2 Compartment

Answer 18

Question 19

F of Oral

Answer 19

Question 20

Fraction excreted oral dose

Answer 20

Question 21

Clearance Oral

Answer 21

Question 22

Renal Clearance

Answer 22

Question 23

Hepatic Clerance

Answer 23

Question 24

Equation for the last portion of the trapezoidal rule of AUC

Answer 24

Question 25

t1/2 equation

Answer 25

t1/2 = 0.693/Kd