Types of hepatobiliary injury

Question 1

representative toxins: amiodarone, CCl4, fialuridine, tamoxifen, valproic acid

Answer 1

Fatty liver

Question 2

representative toxins: acetaminophen, allyl alcohol, Cu, dimethylformamide, ethanol

Answer 2

Hepatocyte death

Question 3

representative toxins: diclofenac, ethanol, halothane, tienilic acid

Answer 3

Immune-mediated response

Question 4

representative toxins: chlorpromazine, cyclosporin A, 1,1-dichloroethylene, estrogens, Mn, phalloidin

Answer 4

Canalicular cholestasis

Question 5

representative toxins: alpha-naphthylisothiocyanate, amoxicillin, methylene dianiline, sporidesmin

Answer 5

Bile duct damage

Question 6

representative toxins: anabolic steroids, cyclophosphamide, microcystin, pyrrolizidine alkaloids

Answer 6

Sinusoidal disorders

Question 7

representative toxins: CCl4, ethanol, thioacetamide, vit. A, vinyl chloride

Answer 7

Fibrosis and cirrhosis

Question 8

representative toxins: Aflatoxin, androgens, arsenic, thorium dioxide, vinyl chloride

Answer 8

Tumors