U4M1 pt1 Flashcards

Cell Cycle Regulation (58 cards)

1
Q

Why do cells divide

A

Reproduce the organism
- prokaryotes and single cell eukaryotes

Eukaryotic cells also divide to
- replace dead cells
- allow the organism to grow

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2
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3
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4
Q

What phases of the eukaryotic cell cycle

A
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5
Q

what is the definition of the cell cycle

A

a period of growth followed by nuclear division and cytokinesis

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5
Q

what is cytokinesis

A
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5
Q

what is mitosis

A

the division of replicated DNA equally and precisely

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5
Q

what type of of cell division results in daughter cells that are exact genetic copies

A

mitosis

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6
Q

what phase of the eukaryotic cell cycle does DNA synthesis occur

A

S phase

in interphase

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7
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7
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8
Q

when are the centrosomes pulled apart in mitosis

A

during prophase

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8
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9
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9
Q

What propels the centrosomes apart from one another during prophase

A
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10
Q

How do the kinetochores of sister chromatids end up facing in opposite directions

A
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10
Q

What role do non-kinetochore microtubules play during mitosis

A
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11
Q

During prometaphase, the sister chromatids jerk back and forth. What causes this back and forth motion

A
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12
Q

How does the size of the daughter cells immediately after cytokinesis compare to the size of the parent cell at the end of G2

A
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12
Q

Cytokinesis divides the original cell into two daughter cells. How do these daughter cells compare genetically

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13
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14
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what phase of the cell cycle do cells spend most of their time
virtually all their time spent Interphase G1 of interphase
19
what is interphase
19
When does interphase begin
as daughter cell from previous division cycle enters initial period of cytoplasmic growth
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what are the internal checkpoints of the cell cycle and what do they do
24
What do cyclins and cyclin dependent kinases control
the internal molecular controls that directly regulate cell division
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what is the concentration of cyclins like in the cell
it flucuates cyclically, activating the CDKs appropriately, tells the CDKs what point in the cell cycle the cell is at
26
what do cyclins and cyclin dependent kinases do
activate/inactivate a large number of proteins associated with cell cycle events
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when is cyclin degraded in the cell cycle
the end of mitosis
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what is the concentratin of CDKs like in the cell
maintained at a constant level throughout the cell cycle
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how much cyclin is in the cell during mitosis
lots, the most it can get
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when is cyclin at its highest concentration in the cell
the middle of mitosis
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when is cyclin at its lowest concentration in the cell
interphase
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how much cyclin is in the cell during interphase
barely any, almost none
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at the G1 checkpoint, what happens if it gets the go ahead
the cell cycle will continue and go on the complete division
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continue on slide 16
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what factors decide whether the cell cycle will continue after the G1 checkpoint
- size - availability of nutriets - DNA damage (specifically p53 gene)
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at the G1 checkpoint, what happens if it does not get the go ahead
it will likely go into G0, a nondividing state
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what's the deal with the p53 gene