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MRCS > UC vs Crohns > Flashcards

UC vs Crohns Flashcards

1
Q

Transmural inflammation

A

Crohns

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2
Q

Fistula 20%

A

Crohns

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3
Q

Peri-anal disease 25% total

A

UC

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4
Q

Peri-anal disease up to 75%

A

Crohns

-if small bowel involved –> 75%

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5
Q

Pseudopolyps

A

UC

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6
Q

Mucosal inflammation

A

UC

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7
Q

Discrete deep ulcers and fissures

A

Crohns

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8
Q

Multiple small ulcers

A

UC

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9
Q

Crypt architectural distortion

A

UC

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10
Q

Cobblestone appearance

A

Crohns

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11
Q

Goblet cell depletion

A

UC

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12
Q

Granulomas present

A

Crohns

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13
Q

Relative risk of colorectal cancer = 2.5

A

Crohns

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14
Q

Crypt abscess

A

UC

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15
Q

Submucosal chronic inflammatory cell infiltrate

A

UC

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16
Q

25% absolute risk of colorectal cancer

A

UC
- if pancolitis
/ 30 years

17
Q

Smoking protective

A

UC

18
Q

Smoking worsens

A

Crohns

19
Q

CARD15 (NOD2), dysregulation of adaptive immunity

IL23R), and deficient autophagy (ATG16L1, IRGM

A

Crohns

20
Q

Primary sclerosing cholangitis

A

UC

21
Q

Rose-thorn ulcers, long

irregular terminal ileal stricture

A

Crohns

22
Q

Loss of haustrations

A

UC

23
Q

Widening of the retrorectal space

A

UC

Due to perirectal inflammation and reduced distensibility of the rectum

24
Q

Colonoscopy should be performed at 2-yearly intervals

A

UC

MRCS (24 decks)

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