Ulcerative Colitis Flashcards Preview

GI: Inflammatory Bowel Disease > Ulcerative Colitis > Flashcards

Flashcards in Ulcerative Colitis Deck (29)
Loading flashcards...
1

more common in ____

males

2

affects the ___ extending proximally

rectum

3

what are the symtoms

- Diarrhoea and bleeding - may have mucous/pus
- Increased bowel frequency - NEED TO FIND OUT HOW OFTEN
- Urgency, tenesmus and incontinence
- Night rising
- Lower abdo pain (LIF)
- (Proctitis can cause constipation)

4

what is important in the history?

Recent travel
Antibiotics
NSAIDS
Family history
Smoking
SKin, eyes, joints

5

what extraintestinal skin manifestations may you get with UC?

erythema nodosum

pyoderma gangrenosum

clubbing

6

what extraintestinal joint manifestations may you get with UC?

- spondylitis, sacroileitis, Peripheral arthritis
- Axial, peripheral joints

7

what extraintestinal eye manifestations may you get with UC?

uveitis

8

what extraintestinal circulation manifestations may you get with UC?

phlebitis

9

may have deranged ___

LFTs

10

may get ____ stones

oxalate renal

11

____ and ____ are GI problems associated with UC

PSC and gallstones

12

what may be present on mouth examination

apthous mouth ulcers

13

what tests would you order to make an exclusion

Stool studies - to exclude campylobacter, c.diff, salmonella, e.coli, amoeba

14

what tests would you do?

blood: FBC, ESR, CRP, U and E, LFT, blood culture

plain AXR

- colonoscopy

15

why do a plain AXR

can be used to rule out perforation and toxic megacolon at first presentation

16

on an AXR you may see -___/____ ___

thumbprinting/ lead piping

17

colonoscopy may show _____ mucosal ulceration where the ulcers have a ___ base

superficial , broad base

18

inflammation in UC is confined to the ___ and ____ except in ____ ____

Inflammation confined to the mucosa and submucosa except in toxic megacolon

19

on colonoscopy may see ___ mucosa and diffuse erythema and may find _______

granular , pseudopolyps

20

what are pseudopolyps?

The repeated cycle of ulceration, alternating with the deposition of granulation tissue during the healing phase, results in the development of raised areas of inflamed tissue that resemble polyps.

21

histologically there is the absence of ___ cells and ____ distortion and may even get crypt ___

histologically there is the absence of goblet cells and crypt distortion and may even get crypt abscess

22

what are the complications of UC?

- colorectal cancer
- also cholangioma - if have PSC
- intractable disease
- toxic megacolon
- blood loss
- electrolyte disturbances
- anal fissures (uncommon)

23

what electrolyte disturbance may arise with UC?

hypokalaemia

24

toxic megacolon requires an emergency_____

colectomy

25

what is the differential diagnosis for UC

- Crohn’s disease
- Indeterminate colitis
- Radiation colitis
- Infectious colitis
- Diverticulitis
- IBS
- Mesenteric ischaemia
- Vasculitis

26

WHAT WOULD MAKE YOU THINK RADIATION colitis instead of UC?

Radiation colitis - if have a history of receiving radiotherapy especially to pelvic area

27

what would make you think infectious colitis instead of UC?

Infectious colitis - history of recent exposure or travel

28

what would make you think diverticulitis instead of UC?

Diverticulitis - older age, fever nausea, diarrhoea or constipation

29

what would make you think mesenteric ischaemia instead of UC?

history of heart disease