UNIT 1 HISTORICAL BACKGROUND Flashcards
Phenol is Bactericidal or Fungicidal at concentrations
1%-2%
Discovered Penicillin in 1928
ALEXANDER FLEMING
Creation of Attenuated Vaccines
LOUIS PASTEUR
Evidence required to establish etiologic relationship between microorganism and disease
Koch’s Postulates
Penicillin Came from the mold
Penicillium rubens
ALEXANDER FLEMING Together with his colleagues ___________ and _________ was credited for the world’s first broadly effective antibiotic substance (penicillin)
Howard Florey and Ernst Boris Chain
Culture of Bacteria using media
Robert Koch
Proponent of Biogenesis
LOUIS PASTEUR
Introduced pasteurization
LOUIS PASTEUR
Developed the antiseptic system of surgery
JOSEPH LISTER
first effective medicinal treatment for syphilis
salvarsan
Phenol is Bacteriostatic at concentrations
0.1-1%
ANTON VAN LEEUWENHOEK is the First person to observe and describe microorganisms and called them as
“animalcules”
Proposed the Germ Theory which suggested that disease is
caused by “invisible living creatures”
GIROLAMO FRACASTORO
Father of Modern Microbiology
LOUIS PASTEUR
LOUIS PASTEUR disproved
Spontaneous Generation
Koch’s Postulates
- Microorganism must be observed in every case of
the disease - It must be isolated and grown in pure culture
- The pure culture, when inoculated in animals must reproduce the disease
- Microorganism must be recovered from the diseased
animal
- Microorganism must be recovered from the diseased
JOSEPH LISTER used this as antiseptic
carbolic acid or phenol
Nobel prize winning German physician-scientist who worked
in the fields of Hematology, Immunology, and Antimicrobial
chemotherapy
PAUL EHRLICH
Father of Protozoology and Bacteriology
ANTON VAN LEEUWENHOEK
Use of Agar and Petri Dish in Cultivating Bacteria
Robert Koch
ROBERT KOCH discovered
Bacillus anthracis and
Mycobacterium tuberculosis
PAUL EHRLICH discovered __________ to treat syphilis in 1909
salvarsan
Fermentation
LOUIS PASTEUR