Unit 1 Introduction Flashcards

(39 cards)

1
Q

what is physiology?

A

study of the normal functioning of a living organism and its component part

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2
Q

what are the key concepts that are important to understanding physiology?

A

-structure and function
-biological energy
-information flow
-homeostasis

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3
Q

what are the levels of living organisms

A

-chemical (atoms and molecules)
-cellular (neuron, lymphocyte)
-tissue (collection of cells)
-organ (structural unit made of tissues)
-organ system (integrated group of organs)
-organisms (individual form of life)

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4
Q

how is physiology an integrative science

A

-considers many different levels of organization
-most current research focuses on molecular and cellular level
-how events in single cell influence everything else

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5
Q

how are cells held together

A

-anchoring junctions
-gap junctions
-tight junctions

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6
Q

what are the 4 tissue types

A
  1. epithelial
  2. connective
  3. muscle
  4. neural
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7
Q

what are the 5 types of epithelia

A
  1. exchange (rapid exchange of material)
  2. ciliated (line airways and female reproductive tract)
  3. secretory (synthesize and release products into the external environment/blood)
  4. transporting (selective transport of material)
  5. protective (found on surface of the body)
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8
Q

what does the epithelial do?

A

-protects the internal environment of the organism
-regulates exchange of material between the external environment and internal environment
-consists of one or more layers of cells connected to one another and to a basal lamina (basement membrane)

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9
Q

what does the connective tissue do?

A

-provides structural support and barriers (extensive extracellular matrix)
-the EMC contains proteoglycans, collagen, elastin, and fibronectin

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10
Q

what are the 5 types of connective tissue

A
  1. loose (elastic tissue)
  2. dense (strength is the primary function) (tendons )
  3. adipose (contains adipocytes)
  4. blood (watery matrix lacking insoluble protein fibers)
  5. supporting (dense substances) (bone and cartilage)
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11
Q

what does muscle tissue do?

A

-ability to contract to produce force and movement

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12
Q

what are the 3 types of muscle?

A
  1. skeletal (responsible for gross body movement)
  2. smooth (responsible for influencing the movemnt of substances into/out of/ within the body)
  3. cardiac (found only in the heart, contraction moves blood through the body)
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13
Q

what does neural tissue do?

A

-carry information from one part of the body to another
-there is very little EMC in neural tissue

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13
Q

what does neural tissue do?

A

-carry information from one part of the body to another
-there is very little EMC in neural tissue

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14
Q

what are the 2 types of neural tissue

A
  1. neurons (carry information as electrical or chemical signals)
  2. glial cells (supporting cells for neurons)
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15
Q

what are the organ systems in the human body

A
  1. nervous system
  2. musculoskeletal system
  3. circulatory system
  4. respiratory system
  5. immune system
  6. endocrine system
  7. reproductive system
  8. digestive system
  9. urinary system
  10. integumentary system
16
Q

what is function?

A

function of a system is the “why”

17
Q

what is mechanism?

A

process of a system is the “how”

18
Q

what is homeostasis?

A

-the maintenance of a relatively stable internal environment
-involves a series of automatic control mechanisms
-oscillation around a set point (and a set point can change with time)

19
Q

what is acclimatization?

A

environmentally induced change in physiological function with no genetic change

20
Q

what are the four basic mechanisms of how cells communicate?

A
  1. gap junctions
  2. contact dependant signals
  3. local communication
  4. long distance communication
21
Q

explain gap junctions

A

-direct cell to cell communication
-occurs via protein channels (connexons) between adjacent cells
-found in many cell types

22
Q

explain contact dependant signal

A

-interaction between two membrane molecules on two cells
-found in immune cells and during development

23
Q

explain local communication

A

-communication with neighbouring cells
-via paracrine and autocrine signals
-chemicals secreted by cells which act on neighbouring cells are known as paracrine signals (immediate vicinity)
-autocrines act on the cell that produces the chemical

24
explain long distance communication
-responsibility of the nervous and endocrine system -nervous system uses combinations of chemical and electrical signals (neurohormones, neurotransmitters) -endocrine system uses chemical signals (hormones)
25
why do some cells respond to a chemical signal and others do not?
1. target cells have various receptor proteins 2. only respond to a chemical signal if they have the appropriate receptor
26
what are receptors?
-usually transmembrane proteins -usually found in plasma membrane but can be intracellular (cytosoloic or nuclear) -membrane spanning receptors have 3 main domains
27
what are the 3 domains of membrane spanning receptors
1. extracellular domain (involved in binding the ligand (chemical signals) 2. trans membrane domain (hydrophobic) 3. intracellular domain (involved in activating the cellular response
28
receptors vs. chemical signals
-it is the receptor not just the signal the determines the type of response -any molecule that can bind with the receptor and induce activity will elicit the response -agonist (mimics primary ligand and activates receptor in the same way (not normal molecule the body produces) -antagonist (binds to receptor but no longer produces a signal)
29
what are the steps of a responses to chemical signals
1. signalling molecules binds to receptor 2. activated receptor interacts with molecules inside the cell to start a signal 3. signal is carried to appropriate place inside the cell (signal transduction) 4. response occurs
30
what is reflex control
-the reaction in one or more organs controlled from elsewhere in the body -can be any long distance path of the nervous and/or endocrine system
31
what is local control
-the effects are exerted on neighbouring cells -ex. paracrine control of blood vessel diameter in response to low O2
32
homeostatic control systems
-stability is result of balance between input and output -negative feedback returns variable to original condition -homeostatic systems maintain similarity not constancy -set points can be reset -some variables are controlled more closely than others -most control systems require communication between cells
33
response loops in reflex control
-start with a stimulus and results in a response -feedback pathways control the response loop -3 types of feedback to regulate response loops
34
what are the 3 types of feedback/control systems to regulate response loops
1. negative feedback 2. positive feedback 3. feedforward control
35
explain negative feedback
-results in change that opposes or removes the signal thus returning the variable to its original value -allows for homeostatic control -keeps system near or at a set point -oscillation around a set-point -ex. blood pressure
36
explain positive feedback
-response sends a signal that reinforces the stimulus -sends the variable further from set point until an external signal turns the response off -ex giving birth
37
explain feedforward control
-anticipatory control -predicts that change is about to happen which starts the response loop and prevents change -ex. thought of food
38
order of response loop
1. stimulus 2. sensor or receptor 3. afferent pathway 4. integrating center (CNS) 5. efferent pathway 6. target or effector 7. response