UNIT 13 AMINOTIC FLUID Flashcards

(30 cards)

1
Q

Which of the following is not a function of amniotic fluid?
A. Allows movement of the fetus
B. Allows carbon dioxide and oxygen exchange
C. Protects fetus from extreme temperature changes
D. Acts as a protective cushion for the fetus

A

B

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2
Q

What is the primary cause of the normal increase in amniotic fluid as a pregnancy progresses?
A. Fetal cell metabolism
B. Fetal swallowing
C. Fetal urine
D. Transfer of water across the placenta

A

C

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3
Q

Which of the following is not a reason for decreased
amounts of amniotic fluid?
A. Fetal failure to begin swallowing
B. Increased fetal swallowing
C. Membrane leakage
D. Urinary tract defects

A

A

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4
Q

Why might a creatinine level be requested on an amniotic
fluid?
A. Detect oligohydramnios
B. Detect polyhydramnios
C. Differentiate amniotic fluid from maternal urine
D. Evaluate lung maturity

A

C

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5
Q

Amniotic fluid specimens are placed in amber-colored tubes
prior to sending them to the laboratory to prevent the
destruction of:
A. Alpha-fetoprotein
B. Bilirubin
C. Cells for cytogenetics
D. Lecithin

A

B

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6
Q

How are specimens for FLM testing delivered to and stored
in the laboratory?
A. Delivered on ice and refrigerated
B. Immediately centrifuged
C. Kept at room temperature
D. Delivered in a vacuum tube

A

A

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7
Q

Why are amniotic specimens for cytogenetic analysis incu-
bated at 37°C prior to analysis?
A. To detect the presence of meconium
B. To differentiate amniotic fluid from urine
C. To prevent photo-oxidation of bilirubin to biliverdin
D. To prolong fetal cell viability and integrity

A

D

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8
Q

Match the following colors in amniotic fluid with their
significance.
___ A. Colorless 1. Fetal death
___ B. Dark green 2. Normal
___ C. Red-brown 3. Presence of bilirubin
___ D. Yellow 4. Presence of meconium

A

2,4,1,3

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9
Q

A significant rise in the OD of amniotic fluid at 450 nm
indicates the presence of which analyte?
A. Bilirubin
B. Lecithin
C. Oxyhemoglobin
D. Sphingomyelin

A

A

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10
Q

Plotting the amniotic fluid OD on a Liley graph represents
the severity of hemolytic disease of the newborn. A value
that is plotted in zone II indicates what condition of the
fetus?
A. No hemolysis
B. Mildly affected fetus
C. Moderately affected fetus that requires close monitoring
D. Severely affected fetus that requires intervention

A

C. MODERATE

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11
Q

The presence of a fetal neural tube disorder may be
detected by:
A. Increased amniotic fluid bilirubin
B. Increased maternal serum alpha-fetoprotein
C. Decreased amniotic fluid phosphatidyl glycerol
D. Decreased maternal serum acetylcholinesterase

A

B

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12
Q

True or False: An AFP MoM value greater than two times the median value is considered an indication of a neural tube disorder.

A

TRUE

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13
Q

When severe HDN is present, which of the following tests on the amniotic fluid would the physician not order to
determine whether the fetal lungs are mature enough to withstand a premature delivery?
A. AFP levels
B. Foam stability index
C. Lecithin/sphingomyelin ratio
D. Phosphatidyl glycerol detection

A

A

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14
Q

True or False: Prior to 35 weeks’ gestation, the normal L/S
ratio is less than 1.6.

A

TRUE

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15
Q

When performing an L/S ratio by thin-layer chromatography,
a mature fetal lung will show:
A. Sphingomyelin twice as concentrated as lecithin
B. No sphingomyelin
C. Lecithin twice as concentrated as sphingomyelin
D. Equal concentrations of lecithin and sphingomyelin

A

C. LECITHIN TWICE AS CONCETRATED

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16
Q

True or False: Phosphatidyl glycerol is present with an L/S
ratio of 1.1.

17
Q

A rapid immunologic test for FLM that does not require
performance of thin-layer chromatography is:
A. AFP levels
B. Amniotic acetylcholinesterase
C. Aminostat-FLM
D. Bilirubin scan

18
Q

Does the failure to produce bubbles in the Foam Stability
Index indicate increased or decreased lecithin?
A. Increased
B. Decreased

19
Q

The presence of phosphatidyl glycerol in amniotic fluid
fetal lung maturity tests must be confirmed when:
A. Hemolytic disease of the newborn is present
B. The mother has maternal diabetes
C. Amniotic fluid is contaminated by hemoglobin
D. Neural tube disorder is suspected

20
Q

A lamellar body count of 50,000 correlates with:
A. Absent phosphatidyl glycerol and L/S ratio of 1.0
B. L/S ratio of 1.5 and absent phosphatidyl glycerol
C. OD at 650 nm of 1.010 and an L/S ratio of 1.1
D. OD at 650 nm of 0.150 and an L/S ratio of 2.0

21
Q

The amount of amniotic
fluid increases in quantity throughout pregnancy, reaching a
peak of approximately

A

800 to 1200 ml

22
Q

An
amniotic fluid volume greater than 1200 mL

A

polyhydramnios

23
Q

whereas amniotic fluid volume less than 800 mL is

A

oligohydramnios

24
Q

Polyhydramnios may be secondarily associated with

A

fetal structural anomalies, cardiac arrhythmias, congenital infections,
or chromosomal abnormalities.

25
Increased fetal swallowing, uri- nary tract deformities, and membrane leakage are possible causes of decreased amniotic fluid
oligohydramnios
26
may be associated with congenital malformations, premature rupture of amniotic membranes, and umbilical cord compression,
oligohydramnios
27
Failure of the fetus to begin swallowing results in excessive accumulation of amniotic fluid (_______) and is an indication of fetal distress,
polyhydramnios
28
A maximum of _____ of amniotic fluid is collected in sterile syringes.
30ml
29
collected can be contaminated by maternal blood, tissue fluid, and cells and are discarded.
first 2-3 ml
30
Creatinine does not exceed 3.5 mg/dL and urea does not exceed 30 mg/dL in amniotic fluid,
TRUE