Unit 2 Targets of Antibiotics

Question 1

Ciprofloxacin

Answer 1

inhibit DNA gyrase

Question 2

Levofloxacin

Answer 2

inhibit DNA gyrase

Question 3

Moxifloxacin

Answer 3

inhibit DNA gyrase

Question 4

Chloramphenicol

Answer 4

inhibits protein synth, 50s

Question 5

Aminoglycoside

Answer 5

inhibits protein synth 30s

Question 6

Clindamycin

Answer 6

inhibit protein synth, 30s

Question 7

Tetracycline

Answer 7

inhibits protein synth 30s

Question 8

Doxycycline

Answer 8

inhibits protein synth, 30s

Question 9

Erythromycin

Answer 9

inhibit protein synth, 50s

Question 10

Azithromycin

Answer 10

inhibit protein synth, 50s

Question 11

Clarithromycin

Answer 11

inhibit protein synth, 50s

Question 12

Name the macrolides

Answer 12

ACE

Question 13

Name the Fluoroquinolones

Answer 13

Ciprofloxacin, Levofloxacin, Moxfloxacin

Question 14

Name the penicillins

Answer 14

Pen G, Pen V, Dicloxacillin, Amoxacillin/Ampicillin, Piperacillin

Question 15

Name the Cephalosporins

Answer 15

Cephalexin, Cefazolin, Ceftriaxone, Cefuroxime

Question 16

Penicillins - MoA

Answer 16

cell wall synthesis inhibitors, stage 3

Question 17

Cephalosporins - MoA

Answer 17

cell wall synth inhibitors, stage 3

Question 18

Vancomycin

Answer 18

cell wall synth inhibitors, stage 2

Question 19

Pen G

Answer 19

cw synth inhibitor

Question 20

Pen V

Answer 20

cw synth inhibitor

Question 21

Dicloxacillin

Answer 21

cw synth inhibitor, penicillinase resistant

Question 22

Amoxicillin/Amp

Answer 22

cw synth inhibitor

Question 23

Piperacillin

Answer 23

cw synth inhibitor, antipseudomonal

Question 24

Clavulanic Acid

Answer 24

beta lactamase inhibitor, add to Amoxacillin

Question 25

Tazobactam

Answer 25

beta lacatamase inhibitor, add to piperacillin

Question 26

What generation? Cefazolin

Answer 26

1st Cephalosporin

Question 27

What generation? Cefuroxime

Answer 27

2nd cephalosporin

Question 28

What generation? Cephalexin

Answer 28

1st Ceph

Question 29

What generation? Ceftriaxone

Answer 29

3rd Ceph

Question 30

Nitrofurantoin

Answer 30

intermediates damage bacterial dna, reduced to active form intracellularly

Question 31

Metronidazole

Answer 31

interferes with dna function, reduced to active form intracellularly