Unit 2: The Nerve Impulse Flashcards
What do neurones do?
transmit impulses to other neurones to effect a response
What does the sodium/potassium pump in the membrane of the axon do to maintain resting potential?
actively transports 3 sodium ions out of the membrane and 2 potassium ions into the membrane.
What gives the sodium/potassium pump energy to transport ions in and out of the membrane
Dephosphorylation of ATP
Describe the charges inside and outside of the membrane of an axon at resting potential
Outside of the membrane more positive than inside which is less positive (so relatively negative)
Why are voltage gated protein channels different to normal protein channels?
because they open / close depending on the charge of the membrane.
What do voltage gate channels do?
Change the permeability of the membrane to certain ions at different voltages.
How do the voltage gated channels maintain resting potential?
The potassium voltage gated channels are open and potassium diffuse out of the membrane down the electrochemical gradient. The Na VG channels are closed.
What charge is the inside of the neurone at resting potential?
-70mV
What is depolarisation?
when energy from an impulse causes the temporary reversal of charges so the inside of the membrane becomes positive and the outside becomes negative.
What happens during depolarisation?
The sodium voltage gated channels open so that sodium ions diffuse in down the electrochemical gradient and the K VG channels close.
What is the charge of the neurone at action potential?
+40mV
What is an action potential?
change in the electrical potential associated with the passage of an impulse along a membrane
What is repolarisation?
when the membrane gets restored back to its original polarity
Describe what happens during repolarisation
When an action potential reaches +40 mV, it causes the sodium VG channels to close and the potassium channels to open. K ions diffuse out the membrane down the electrochemical gradient
What is hyperpolarisation?
when the axon reaches a more negative charge inside usual (at resting potential).
What is charge inside of the neurone when hyperpolarisation occurs?
-90mV
Why do neurones become hyperpolarised?
there is a delay in the closing a potassium voltage gate channels.
How are nerve impulses started?
by receptor cells in living organisms
How are nerve impulses propagated along an neurone?
an action potential starts in one part of the axon which causes it to become depolarised. This acts as a stimulus for the next area to become depolarised. The area behind eventually becomes repolarised and then goes back to resting potential.
What is saltatory conduction?
When action potentials jump from one node of ranvier to another
What is the advantage of saltatory conduction?
impulses travel a lot faster
Why do action potentials only occur at the nodes of ranvier in a myelinated axon?
Because the myelin sheath acts as an electrical insulator, preventing action potentials from forming along the myelinated parts of the neurone.
What is the refractory period?
the resting period of an ion channel. After an ion channel has opened, there is a rest period before it can open again.
What prevents action potentials travelling in both directions?
the refractory period