Unit 3 From PPQs Flashcards

1
Q

Statistically significant difference

A

Error bars do not overlap

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2
Q

Negative correlation

A

One factor increases, the other decreases

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3
Q

One factor increases, the other decreases

A

Negative correlation

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4
Q

Positive correlation

A

One factor increases, the other does too

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5
Q

One factor increases, the other does too

A

Positive correlation

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6
Q

Scattergraph reliability

A

Not reliable if many points lie far from line of best fit

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7
Q

Not reliable if many points lie far from line of best fit

A

Scattergraph reliability

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8
Q

Advantages of in vivo

A

Allows possible side effects to be shown

Allows effect of the drug/treatment on whole organism to be shown

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9
Q

Purpose of including a control

A

Comparison between drug and absense of drug

Gives baseline to measure the effect of the drug against

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10
Q

Comparison between drug and absense of drug

Gives baseline to measure the effect of the drug against

A

Purpose of placebo

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11
Q

Issue with patients administering drugs themselves in a drug trial

A

Decreases reliability as they may forget or not inject correctly

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12
Q

Purpose of randomised block design

A

Control confounding variables

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13
Q

Downside of randomised control groups

A

More time consuming

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14
Q

Stratified sampling

A

Population divided into categories and sampled proportionally

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15
Q

Population divided into categories and sampled proportionally

A

Stratified sampling

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16
Q

Why don’t placebos work for animals

A

They have no expectation

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17
Q

Reducing harm when using animals

A

Refinement - harm minimised

Reduction - minimum number of animals for validity

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18
Q

Do you need controls for each treatment

A

Yes if there is a different number of participants in each group

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19
Q

Review article

A

Compiles summarises of recent research in a particular field

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20
Q

Compiles summarises of recent research in a particular field

A

Review articles

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21
Q

Downside of observational studies

A

Cannot show causation

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22
Q

Accurate

A

Data close to true value

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23
Q

Data close to true value

A

Accurate

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24
Q

Precise

A

Dats has little variation

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25
Data has little variation
Precise
26
Reliable
Replicates have consistent values
27
Replicates have consistent values
Reliable
28
Valid
Controlling variables
29
Controlling variables
Valid
30
Systematic sampling
Members of a population are selected at regular intervals
31
Members of a population are selected at regular intervals
Systematic sampling
32
Ecological sampling
Splitting up area and choosing random spots with randomised number generator
33
Splitting up area and choosing random spots with randomised number generator
Ecological sampling
34
Random sampling
Members of population have equal chance of selection
35
Members of population have equal chance of selection
Random sampling
36
Confidence interval
Indicates variability of data around mean
37
Indicates variability of data around mean
Confidence interval
38
“Statistically significant difference”
Must say increase or decrease!
39
Pilot study
Allows modifications of experimental design
40
Allows modifications of experimental design
Pilot study
41
Representative sample must have what
Same mean as population as a whole
42
Purpose of double blind design
Prevent bias
43
Confounding variable
Any variable besides the independent that may affect dependant variable
44
Any variable besides the independent that may affect dependant variable
Confounding variable
45
Experiment that is developing a technique within a larger investigation
Pilot study
46
Ethical considerations when using humans
Informed consent Right to withdrawal data Confidentiality
47
Causes of negative result
Experiment carried out wrong Hypothesis is wrong
48
Negative result
Finding no effecr
49
Positive control
Assesses the test validity Checks the system can detect a positive result
50
Assesses the test validity Checks the system can detect a positive result
Positive conrrol
51
Negative control
Checking false positives don’t occur An absence of treatment
52
In vivo
Whole, living organism
53
In vitro
Preforming procedure in a controlled environment outside of a living organism
54
In vivo advantages and disadvantages
Provides data for effects in whole organism Expensive and time consuming Difficult to control variables
55
In vitro advantages and disadvantages
Simpler and less expensive Interpretation of results is simpler Difficult to extend results to whole organism or different species Difficult to model complex interactions
56
More variation in population requires what
Larger sample size
57
Peer reviewed
Articles evaluated by experts in the field
58
Articles evaluated by experts in the field
Peer reviewed
59
Epidemiology
Study of outbreak and spread of diseases
60
Study of outbreak and spread of diseases
Epidemiology
61