Unit 4

Question 1

Mutation that changes amino acid coding codon to a stop codon

Answer 1

Nonsense

Question 2

Mutation that arise in nature

Answer 2

Spontaneous

Question 3

Thymine dimers

Answer 3

Two thymines on same strand adjacent to each other

Question 4

Will not pass to offspring

Answer 4

Somatic

Question 5

Tautomeric shift

Answer 5

Transition mutations

Question 6

Membrane protein found entirely outside bilayer

Answer 6

Lipid anchored protein

Question 6

Glycerol +1 phosphate group +2 fatty acids

Answer 6

Phosphatidic acid

Question 7

Penetrates into hydrophobic part of lipid bilayer

Answer 7

Integral protein

Question 8

Sphingosine plus fatty acid linked to sphingosine

Answer 8

Ceramide

Question 8

Most function of cell membrane are performed by

Answer 8

Proteins

Question 9

With what structure is the RER often seen to be continuous as seen by its association with ribosomes?

Answer 9

The outer membrane of the nuclear envelope

Question 9

Stealth liposomes protection

Answer 9

Synthetic polymer coating

Question 10

Two sites where protein synthesis can occur

Answer 10

Cytosolic surface of RER and free ribosomes

Question 11

Order of passage of materials produced in biosynthetic pathway is

Answer 11

Endoplasmic reticulum, golgi complex, secretory vesicle, plasma membrane

Question 12

Binding of SRP to growing polypeptide and ribosome cause

Answer 12

Protein synthesis to cease temporarily

Question 13

Midfielder secretory protein are destroyed in

Answer 13

Cytosol

Question 14

Golgi cisternae are transient structures that form at the cis face of the stack by fusion of membranous carriers

Answer 14

Cisternal maturation model

Question 15

Moves material in retrograde direction from ERGIC and Golgi stack backwards to ER

Answer 15

COPI-coated vesicles

Question 16

Directs movement of vesicles through the cytoplasm to final destination

Answer 16

Microtubules and microfilaments

Question 17

BiP

Answer 17

Recognize and bind to unfolded or misfolded proteins and help them attain their native structure

Question 18

Germ cell mutations

Answer 18

Every cell of next generation

Question 19

Multiple contiguous amino acid changes in proteins

Answer 19

Frameshift

Question 20

Phospholipid are

Answer 20

Amphipathic

Question 21

Integral proteins

Answer 21

Do not interact with DNA

Question 22

Organelles of endomembrane system include

Answer 22

Endoplasmic reticulum, lysosomes, Golgi complex

Question 23

Endocytic pathway

Answer 23

Outside to inside of cell

Question 24

Smooth Endoplasmic

Answer 24

Detoxifies drugs synthesizes steroid hormones and stores ions

Question 25

Move newly synthesized phospholipids from the half of the bilayer facing the cytosol into the opposite leaflet of the membrane bilayer

Answer 25

Flippases

Question 26

Involves a synthesis of more chaperones in the ER, is inhibited by BIP molecules, occurs when there are too many misfiled proteins in the ER, and inhibits enzymes involved in protein synthesis

Answer 26

Unfolded protein response UPR

Question 27

Membrane vesicles with their enclosed cargo bud from the edges of the ER and travel to the

Answer 27

Golgi complex

Question 28

Molecular chaperones in the rough ER

Answer 28

Bind to misfolded proteins, and help them fold into their correct three-dimensional structure

Question 29

Long, hollow, unbranched tube with walls, composed of tubulin subunits

Answer 29

Microtubules

Question 30

Which element of the cytoskeleton is found in the cytoplasm and the nucleus?

Answer 30

Intermediate filaments

Question 31

What part of the molecular motor kinesin is responsible for binding to the cargo to be hauled?

Answer 31

The fan shaped tail

Question 32

Move progressively along a microtubule toward the polymers minus end, modules are organized in the shape of a wheel, and it is fundamentally different structure from both myosin and kinesin.

Answer 32

Cytoplasmic dynein