Untitled Deck Flashcards
(104 cards)
Histamine:
Stored in mast cells (below the respiratory mucosa)
Histamine-1 receptors:
Controls smooth muscle contracƟon
Drugs that antagonize H-1 receptors are called:
anƟhistamines
Histamine -2 receptors:
Are in the stomach
GI tract and are responsible for increasing gastric secreƟons
Drugs that antagonize H-2 receptors block acid producƟon
Example: Tagamet
Prilosec
AnƟhistamine side effects:
Dry mouth
Dry throat
Altered coordinaƟon
SedaƟon
Nasal decongestants:
Alpha adrenergic
VasoconstricƟon:
Reduces blood flow
Reduces inflammaƟon (swelling)
They are Available as nasal sprays
Phenylephrine is the Common OTC ingredient
Why is it important for a paƟent receiving systemic corƟcosteroids to wean their dosage when
disconƟnuing therapy: