Urinary Histology Flashcards
(40 cards)
What does the Renal corpuscles include and where are they positioned in the kidney?
The Glomerulus and Bowmans Capsule
Cortex
What constitutes and nephron?
Renal corpuscle
PCT
Loop of Henle
DCT
What are the Ducts of Bellini?
Papillary ducts represent the most distal portion of the collecting duct system. They receive renal filtrate (precursor to urine) from several medullary collecting ducts and empty into a minor calyx.
What is the vascular pole of the glomerulus?
Where the afferent and efferent arterioles commuinicate with the gomerulus
What is the urinary pole of the glomerulus?
Where the golermulus commuincates with the PCT
What is the function of the renal corpuscle?
To produce ultrafiltrate of plasma
What is Bowman’s capsule?
It is a cup like structure that encloses the glomerulus
What is the parietal layer of the Bowman’s capsule?
A single layer of simple squamous epithelium. Does not function in filtration. The layer makes a funnel to collect the ultrafilterate which drains into the PCT at the urinary pole
What is the visceral layer of Bowman’s Capsule?
The Visceral layer of bowman’s capsule wraps around the capillary endothelium and is made of podocytes.
What is the filtration barrier produced by?
Capillary endothelium and visceral layer of Bowmans capsule
What about the capillaries allows the blood to be filtered out?
They are fenestrated and contain podocytes which invest in the capillary endothelium
What make the filtration slits?
The spaces between the podocyte processes
What do the endothelium and podocytes share?
A basement membrane
List 3 things of note about the very leaky filtration barrier?
Podocytes with foot processes
Fenestrated endothelium
Shared basement membrane
what epithelia does the PCT have?
Simple cuboidal epithelium
with a pronounced brush border
What is the longest and most convoluted section of the tubule?
PCT
Where does reabsorption begin?
PCT
What does the loop of henle consist of? (4 parts)
Pars recta
Thin descending limb
Thin ascending limb
Thick ascending limb
What epithelium does the thin descending/ascending limb of the Loop of Henle have?
Simple squamous epithelium, NO brush border
looks a lot like a small capillary but there are no RBCs
Does active transport occur in the thin descending/ascending limb of the loop of henle?
No.
NO ACTIVE TRANSPORT
Where is the loop of henle located?
Dips in to the medulla (in juxtamedullary nephrons, its much longer and does much deeper into the medulla)
What epithelium does the thick ascending limb of the loop of henle contain?
simple cuboidal epithelium
NO brush border
Does active transport occur in the thick ascending limb of the loop of henle?
YES
Where is the DCT located?
Cortex
