Urogynae Flashcards
(38 cards)
Mesh
- Issues
High reoperation rate
urinary incontinence
mesh exposure - 8-15%
high rates of bladder injury
SUI
Prolapse in other sites.
Mesh can now only be used under the therapeutic goods administration special access scheme - in a clinical trial
Much of the scientific evidence used to justify the use of early transvaginal meshes for prolapse isn’t applicable to the newer, lightweight transvaginal permanent meshes.
Informed patient consent for mesh
Inform of withdrawal of mesh products for prolapse repair - limited robust data available on efficacy and safety
Woman who are at risk of recurrent vaginal prolapse and are suitable for mesh need to be in a clinical trial
Only operate on someone with symptoms (little data to recommend treating asymptomatic women)
Alternatives need to be discussed: pelvic floor muscle training, pessaries
Other alternative surgical treatments should be discussed: conventional native tissue repair, abdominal sacrocolpopexy
Risks: mesh exposure / erosion, vaginal scarring/ stricture, fistula formation, dyspareunia, unprovoked pain at rest - can occur many years later
Additional surgeries may be required for mesh complications. Complete removal sometimes is not possible
Surgical training for mesh
Urogynae subspeciality or close attendance at hands on workshops multiple occasions and obserbation of theatre cases
Surgeons should keep themselves up to date in each kit
Regular surgeries
Cytoscopy
Knowledge fo complications
complications need to be logged under MEDSAFE
Who would benefit from TV mesh implant?
Minimal data
those at increased risk of recurrent prolapse - obese, young, chronically raised abdominal pressure (asthma, constipation), stage 3-4 prolapse
What are the three types of pessaries
Support: ring / gehrung
Space occupying (stages III-IV, not usually used if sexually active): gelhorn, shelf, donut cube (needs to be removed every day)
Incontinence with modification: contiform
Advantages and disadvantages of pessaries
Advantages: high levels patient satisfaction, avoids surgery, cheap
Disadvantages: vaginal discharge, ulcerations (vesicovaginal, rectovaginal fistulae), embedded, expulsion, discomfort
Review 1/12 to ensure happy with it and then review annually if self management (can take out herself) or 6 monthly if supportive pessary, 3-4 month if occlusive pessary
Surgical options for uterine prolapse
Vaginal hysterectomy
Abdominal sacrohysteropexy
SSF
Colpocleisis
Mmemonic to explain procedure
P - procedure
R - Reason
E - Expect
P - Probability of cure
A - Alternatives
R - Risks
E
Vaginal hysterectomy - PREPARE
P - vaginal hyst
R - Mid compartment prolapse, HMB, Hyperplasia
Fewer complications, shorter healing time, less pain, less scarring, a lower chance of infection, less risk of hernias, and faster return to activities. Also, a prolapsed uterus is easier to access via the vagina
E - 1 night in hospital, IDC, 2-6 weeks off work, 6 weeks no heavy lifting, browny discharge up to 6 weeks, no intercourse 6 weeks
P - 85% of woman will not require further intervention for their prolapse
A - TLH, TAH, SSF, sacrocolpoplexy
R: GA risks, VTE, bleeding (0-10% RBC) and haematoma (10%), infection, UTI (6-20%), injury to adjacent organs (2%, incl fistula), urinary retention (10-15%), urinary incontinence (if was occult prior to surgery, 40-45%)
E???
Vaginal hysterectomy - steps
Pre op evaluation for fitness for surgery
Informed consent
Sign in: introductions, patient risk factors, HCG status, allergies
GA
Abx
WHO time out
Prep and drape
BM
IDC
Speculum, 2 littlewoods to anterior and posterior lip of cervix
Hydrodissect with local anaesthetic with adrenaline and saline
Circumferential incision at junction of cervix to vaginal mucosa
Blunt and sharp dissection to reflect bladder and elevate away from surgical field with retractor and then enter uterovesical peritoneum
Blunt and sharp dissection into POD and metzenbaum scissors used to enter peritoneum
Ligation of 3 main pedicles on each side: uterosacral, uterine artery, ovarian pedicles (IP including fallopian tube, ovarian and round ligaments)
Uterosacral ligament pedicles are tagged with long sutures
Check ovaries to ensure normal
Check for haemostasis at all pedicles.
Oppose uterosacral ligaemtns using suture lengths and secure to posterior vaginal vault with MAYO needle to allow for vaginal support. (McCalls caldoplasty)
Close vaginal vault with interrupted mattress sutures or continuous locked suture.
Vaginal pack with ovestin for added haemostasis
Post procedure
- Remove IDC and pack day 1
Early mobilization
Thromboprophylaxis
Pain management
E+D as tolerated
Debrief
Post op instructions: driving, constipation, heavy lifting
Clinic FU 4-6 weeks, histo
Abdominal sacrohysteropexy / sacrocolpopexy - PREPARE
P - open or laparoscopic for conservation of uterus. Sutures or mesh can be attached inferiorly to the junction of the cervix and uterus (and uterosacral ligaments) and superiorly to the anterior longitudinal sacral ligament over the first or second sacral vertebra
- Synthetic mesh - woven polypropylene
- Mesh is covered by peritoneum at end.
R - Mid compartment prolapse
E - 1-2 nights in hospital, IDC, 4-6 weeks off work, 6 weeks no heavy lifting
P - 80-90% of women are cured of their prolapse symptoms (vault prolapse - 90-98% success rate)
A - Vag hyst, SSF
R - Pain (generally or dyspareunia - 2-5%)
- Mesh exposure 2-4%
- Damage to bladder, bowel, ureter (1-2%)
- Changes in bowels - constiaption etc. 2-3%
- Changes in urination up to 10% e.g. slow emptying, retention. Usually resolves after a few weeks
- GA risks
- VTE risks
- Bleeding
- Infection
E???
Steps of sacrocolpopexy / hysteropexy
Pre op evaluation for fitness for surgery
Informed consent
Sign in: introductions, patient risk factors, HCG status, allergies
GA
Abx
WHO time out
Lithotomy
Prep and drape
BM
IDC
Place vaginal probe if no uterus
Pfannenstiel incision or laparoscopic entry
Identify ureters
Incise posterior peritoneum (retroperitoneum) over the sacral promontory and dissect inferiorly clearing the periosteum of connective tissue
Incise over the vaginal apex to enter vesicouterine space and reflect bladder caudally if no uterus
Place 3 rows of sutures down the posterior vaginal wall and 2 rows of sutures down anterior vaginal wall to correct anterior and posterior compartment prolapse
OR if uterus, attached mesh to anterior and posterior uterus
Secure mesh to anterior longitudinal ligament under minimal tension at level of S1 avoiding vessels
Confirm haemostasis
Close peritoneum overlying sacral promontory
Close abdomen
Post procedure
- Remove IDC day 1
Early mobilization
Thromboprophylaxis
Pain management
E+D as tolerated
Debrief
Post op instructions: driving, constipation, heavy lifting
Clinic FU 4-6 weeks
Sacrospinous fixation - PREPARE
P - SSF - cervix attached to sacrospinous ligament. Through a cut in the vagina, stitches are placed into the sacrospinous ligament int he pelvis and then to cervix or vaginal vault (permanent or absorbable sutures). Eventually they are replaced by scar tissue.
R - For mid compartment prolapse
E - IDC, pack, 2-4 weeks off work, 6 weeks no heavy lifting, 6 weeks no intercourse
P - 80-85% chance of cure
A - Sacrohysteropexy / colpopexy, colpocleisis, Vag hyst
R - GA, VTE, Bleeding, Infection, Bladder infection (6%), buttock pain (10-18%, majority will get better on its own. Pudendal neurovascualr damage - differing courses of pudendal nerve - place sutures 2cm medial to ischial spines)), constipation, dyspareunia, injury to adjacent structures, SUI (33% - occult prior), bladder emptying difficulty 10%, cystocele formation (20-30% - as exagerated horizontal axis of vagina so anterior compartment of vagina more susceptible to intrabdominal pressure)
Steps of SSF
Pre op evaluation for fitness for surgery
Informed consent
Sign in: introductions, patient risk factors, HCG status, allergies
GA
Abx
WHO time out
Lithotomy
Prep and drape
BM
IDC
Open posterior vaginal wall after hydrodissection with LA with adrenaline
Retract the rectum towards the patient’s left side, away from operative field
Use blunt dissection to enter the right pararectal space to access the ischial spine
Place a retractor at 12 oclock to hold the cardinal ligament containing the ureter out of the operative field
Identify and expose the sacrospinous ligament removing any connective tissue
Place a 2-0 PDS suture using Capi ligature carrier, aiming for mid portion of the sacrospinous ligament 2-3cm medially from the ischial spine and pull through
Repeat with second suture if unilateral procedure
With a free needle (MAYO), secure the suture to the undersurface of the vaginal vault or cervix and tension to reduce prolapse. Tie suture ends
Close the posterior vaginal wall with continuous locked 2-0 Vicryl
Perform rectal exam
Place vaginal pack for haemostasis
Post procedure
- Remove IDC and pack day 1
Early mobilization
Thromboprophylaxis
Pain management
E+D as tolerated
Consider routine laxatives
Debrief
Post op instructions: driving, constipation, heavy lifting
Clinic FU 4-6 weeks
Colpocleisis - PREPARE
P - closure of the vagina - removal of vaginal mucosa and inversion of the vagina (sewing the back and front wall together) using purse string sutures. Highly effective but rate of reoperation unknown. Often combined with perineorraphy.
R - mid compartment prolapse
E - 1 - 2 nights hospital, IDC, +/- vaginal pack, 6 weeks off work, intercourse, heavy lifting
P - 90-95%
A - SSf, sacrocolpopexy / hysteropexy, vag hyst
R -
GA risks, VTE, bleeding, wound infection, bladder infection (6%), pain (particularly if haematoma in a trapped space), rectal pressure - this decreases over time, bladder and bowel injury, 1/10 women feel dissatisfied with the procedure
1/5 regret procedure as sexual intercourse is not possible after this operation.
Steps of a colpocleisis
Pre op evaluation for fitness for surgery
Informed consent
Sign in: introductions, patient risk factors, HCG status, allergies
GA
Abx
WHO time out
Lithotomy
Prep and drape
BM
Apex of prolapse grasped with Allis clamp and two rectangular sections of vaginal mucosa, one anteriorly and one posteriorly are outlined for dissection
Hydrodissection
Denude vaginal epithelium, sharp dissection used to spearate vaginal epithelium from fibromuscular CT
Delayed absorbable suture such as Vicryl used to imbricate a tunnel on either side, followed by imbrication of the cervix
Box sutures are used
Once prolapse is reduced, the vaginal epithelium is approximated with an interrupted or running fashion with a delayed absorbable suture
Cystoscopy the performed
Perineorrhaphy performed to reduce lenght of genital hiatus
Rectal exam
Post procedure
- Remove IDC and pack day 1
Early mobilization
Thromboprophylaxis
Pain management
E+D as tolerated
Consider routine laxatives
Debrief
Post op instructions: driving, constipation, heavy lifting
Clinic FU 4-6 weeks
Anterior colporrhaphy - PREPARE
P - Anterior repair: midline incision in anterior vaginal wall mucosa, push back bladder through dissection and then plicate endopelvic fasica to provide support and elevate bladder and anterior vagina.
R - anterior compartment prolapse
E - 1 night in hospital, IDC, pack in
P - 70 - 90%
A - SSF, pessary, paravaginal repair (corrects lateral defects by reattaching lateral vaginal sulcus to ATFP / white line), abdominoperineal or four corner repair - sutures to paraurethra and 2 more proximally in vaginal wall –> connected to sheath, mesh repairs - not recommended - 8-15% exposure
R - GA, VTE, bleeding (1% RBC), post op infection, bladder infection (6%), dyspareunia, damage to bladder or ureters, incontinence (occult), constipation
Anterior repair - steps of operation
Pre op evaluation for fitness for surgery
Informed consent
Sign in: introductions, patient risk factors, HCG status, allergies
GA
Abx
WHO time out
Lithotomy
Prep and drape
BM
Simms
Grasp apex of repair with allis and hydrodissect the anterior vaginal wall with diluted local anaesthetic with adrenaline
Make vertical incision from the apex to within 1cm of the external urethral meatus
Using sharp and blunt dissection reflect vaginal mucosa off the underlying fascia leaving the fascia attached to the bladder
Extend laterally in an avascular plane toward each pubic rami
Plicate fascia using interupted mattress sutures 2/0 PDS from the apex to the urethral meatus
Consider conservative trimming of redundant anterior vaginal mucosa
Close the anteiror vaginal wall with 2/0 vicryl continuous locked suture
Pack
IDC
Cystoscopy
Post procedure
- Remove IDC and pack day 1
Measure of void and PVR x 1
Early mobilization
Thromboprophylaxis
Pain management
E+D as tolerated
Consider routine laxatives
Debrief
Post op instructions: driving, constipation, heavy lifting
Clinic FU 4-6 weeks
Posterior colporrhaphy + perineorraphy - PREPARE
P - posterior repair - a procedure to repair or reinforce the fascial support layer between rectum and vagina
R - posterior compartment prolapse
E - 1 night stay in hospital, IDC, pack
P - 80-90%
A - Pessary, mesh, site sepcific fascial defect repair , transanal repair performed by colorectal surgeons
R - GA, VTE, bleeding (1% risk RBC), post op infection, bladder infection (6%), constipation, dysapreunia, injury to rectum
E - WrittEn info
Steps of posterior repair and perinorraphy
Pre op evaluation for fitness for surgery
Informed consent
Sign in: introductions, patient risk factors, HCG status, allergies
GA
Abx
WHO time out
Lithotomy
Prep and drape
BM
Grasp apex of vaginal repair and hydrodissect the posterior vaginal wall with dilute local anaesthetic with adrenaline
Grasp perineum ~2cm laterally either side of the midline
Infiltrate with local anaesthetic and make transverse incision
With countertraction use metzenbaum scissors to dissect proximally toward apex in a vertical fashion incising the vaginal skin as you go
Use blunt and sharp dissection to reflect the underlying fascia off the vaginal mucosa laterally to the level of the pararectal space
Site specific plication of perirectal fascia with 2/0 PDS
Consider conservative trimming if redundant posterior vaginal mucosa
Close vaginal mucosa continuous locked suture with 2/0 vicryl
Assess need for perineorraphy
Diamond incision at the perineum
Re approximate the perineal bulk with interupted sutures and then close the skin with subcuticular sutures
Perform PR
Vaginal pack for haemostasis
Post procedure
- Remove IDC and pack day 1
Measure of void and PVR x 1
Early mobilization
Thromboprophylaxis
Pain management
E+D as tolerated
Consider routine laxatives
Debrief
Post op instructions: driving, constipation, heavy lifting
Clinic FU 4-6 weeks
Examination for urinary incontinence
BMI
Abdo and pelvic exam - masses, POP, cough test for SUI
Vaginal exam: atrophy, pelvic floor strength (0 = no contraction, 1 = flicker, 2 = weak, 3 = moderate, 4 = good, with lift, 5 = strong, also note duration of contraction
Neuro exam - S2-4 - deep tendon reflexes at knee and ankle
Cognitive assessment
Cough test (full bladder) - reduce POP to assess for occult SUI also, performed in supine and upright positions
Ix for UI
Urinalysis
PVR
Pad test - quantify urine loss by weighing
Urethral mobility
USS
Cystoscopy if suspected urethrovaginal / vesicovaginal fistula, pain or recurrent UTI. Mandatory in women with haematuria persistent -> bladder biopsy
EMG: can be used to assess pelvic floor denervation in women with UI or POP
Urodynamics
Describe urodynamics
Functional assessment of bladder and urethral function
Demonstrate an abnormality of storage or voiding
Consider if conservative management unsuccessful, mixed symptoms, surgical treatment anticipated, having surgery for a large prolapse, history of voiding dysfunction
Uroflowmetry: measure of flow rate over time (max and average flow rate, flow time, total volume voided)
- <15mL/sec abnormal
>40mL/s may indicate decreased outlet resistance (SUI)
Normal flow pattern bell shaped curve
Residual measured at end
Cystometry
- Pressure volume relationship of the bladder during filling and voiding
concurrent measurement of intravesical and abdominal pressures using catheters inserted into bladder and rectum or vagina.
- detrusor pressure = Pves - P abd
- notify of first desire to urinate, normal desire and urgency
Filling stops at 500mL unless patient reaches max bladder capacity earlier
Provocative measures - coughing, valsalva etc - used to promote leakage (urodynamic SUI if occurs in absence of detrusor activation)
Non surgical interventions for UI
Conservative
- Reduce fluids
- Reduce caffeine / alcohol
- Diet advice to avoid constipation
- Weight loss
- Smoking cessation
- Review drugs
Behavioural therapy (aim to improve central control of micturition)
- Bladder retraining for overactive bladder (urge on filling without overactive bladder) - voluntary and repetitive efforts to defer urination and aim to increase intervals e.g. every hour for first week, then increase by 15-30mins each week until reach 3-4 hours. Requires patient compliance and motivation.
- Biofeedback - vaginal or rectal pressure sensors worn - patient can visualize or hear or feel increase in pressures and then can conciously inhibit them
- Hypnotherapy - OAB thought to be exacerbated by underlying pyschological factors
- Acupuncture
Physical therapies
- PFMT - 8 x on three occasions 55% reported cure or improvement
- Vaginal cones - retain in vagina when walking (no better than PFMT alone)
- Functional electrical stimulation: TENS –> inhibits detrusor muscle in DO, in SUI it directly stimulates Pelvic floor muscles
Pharmacological
- Antimuscuranic / acetylcholine meds
- SE: dry mouth, blurred vision, tachycardia, drowsiness, constipation, CNS issues
- Oxybutynin 5mg TDS -> dry mouth +++
- Solifenacin - better tolerated, 5mg OD. Efficacy after 1 week and stable after 12 weeks
- Mirabegron
- Desmopression (DDAVP) - synthetic analogue of vasopressin which inhibits diuresis but avoids vasopressive effects, used at night in patients with nocturnal polyuria, reduces nocturia by 50%. be aware of hyponatraemia
- Oestrogens - some RCT evidence for OAB, no evidence in SUI
- TCA - sE ++