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Flashcards in urologic cancers Deck (7)
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1
Q

risk factors renal cell carcinoma

A
Renal Cell Carcinoma (85%) of kidney cancers
Risk factors:
Smoking*
Obesity*
Age
Male
Genetics
2
Q

clinical manifestations renal cell carcinoma early and late

A

Early manifestations?
- none, usually undiagnosed

Late manifestations:
CVA tenderness
Hematuria
Palpable abdominal mass

3
Q

tx renal cell carcinoma

A

Symptoms r/t metastases:
- s/s r/t disease traveling to lungs and/or bones

Chemotherapy?

  • resistant to traditional chemo
  • surgery to remove kidney
4
Q

bladder cancer - urothelial carcinoma (90%)

risk factors

A

4th most common cancer in MEN
lining within the bladder

risk factors
Smoking*
Male
Occupations with exposure to toxins
Low fluid intake
5
Q

clinical manifestations bladder cancer

A

Early symptoms:
Hematuria
- need UA

Later symptoms: similar to UTI
Frequency
Urgency
Dysuria

6
Q

how to tx bladder cancer

A

Chemotherapy- depends on the stage!
Stage 1 = Intravesical chemo - stays local to bladder

Advanced stages = Systemic chemo

7
Q

what is intravesical therapy for early stage (stage 1) bladder cancer

A

BCG Vaccine (6 – 12 weeks)
MOA: Stimulates a local inflammatory response in bladder

Adverse effects:
Bladder irritation!
Risk of systemic infection

Patient instructions:
Empty bladder
Dwell time = __2_ hours
Change positions q _15__ minutes

Safety precautions?

  • live virus, NO IMMUNOCOMPROMISED PT
  • disinfect urine after 6 hours