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Flashcards in UsefulNotesDrugs Deck (24):
1

Useful notes on Midazolam

synergy with narcotics, same IV dose regardless of weight

2

Useful notes on Fentanyl

bradycardia > morphine, synergism with benzos, 100x potent as morphine, hemodynamic stability

3

Useful notes on Morphine

often diluted from 10 mg/ml to 1 mg/ml

4

Useful notes on Hydromorphone

not as much PONV as morphine

5

Useful notes on Naloxone

dilute 0.4 mg vial in 10 ml and give 1 ml at a time

6

Useful notes on Propofol

burns on injection, decreases PONV, short duration from redistribution, dose dependent decrease in respirxn, little analgesia

7

Useful notes on Etomidate

cardiovasvular stability, used with bad hearts or HTN

8

Useful notes on Ketamine

nystagmus, prolongs SUX duration

9

Useful notes on Succinylcholine

causes fasciculations, metabloized by plasma cholinesterase, many adverse side effects

10

Useful notes on Rocuronium

increased duration with liver disease and pregnancy, metabolized by liver/kidneys, use TOF for maint and give 1 ml at a time

11

Useful notes on Vecuronium

hardly used for intubation b/c of long onset, use TOF for maint and give 1 ml at a time

12

Useful notes on Cisatracurium

good for renal/hepatic dysfunction, undergoes Hoffman degradation

13

Useful notes on Neostigmine

dosage based on twitch monitor, BLUDS caused at muscarinic cholinergic receptor sites

14

Useful notes on Glycopyrrolate

used specifically to counteract BLUDS, used w/ neostigmine b/c of similar onset/duration, 80 kg pt -> 8.0 -> 4.0 ml neo, 4.0 ml glyco

15

Useful notes on Epinephrine

effects ? & ? receptors

16

Useful notes on Ephedrine

mainly indirect action by causing NE release

17

Useful notes on Phenylephrine

direct acting binds to ? receptors, caution w/ bad hearts b/c of increased afterload, no ? effect, occ. combined with glycopyrrolate

18

Useful notes on Esmolol

fast onset/short duration, works only on ?1 receptors of heart ? ?HR/contractility ? ?BP, metabolized by plasma cholinesterase

19

Useful notes on Metoprolol

same effect as Esmolol, but lasts longer

20

Useful notes on Labetalol

?:? antagonism 7:1, vasodilation from blocking ?1

21

Useful notes on Nitroglycerin

fast onset/short duration, no effect on heart only vasculature, mainly venous side, ? ventricular wall tension

22

Useful notes on Hydralazine

no effect on heart only vasculature, mainly arterial side, long duration undesirable with blood loss

23

Useful notes on Ondansetron

give 30 min before emergence, have PO version for morning sickness, sometimes pushed with induction for short cases

24

Useful notes on Droperidol

used mainly as a secondary to Zofran