usmle 2 Flashcards

(49 cards)

1
Q

a) Mitral Stenosis?
b) PMHx?
c) Jones Criteria for Rheumatic Fever?
d) Sound?
e) Tx?

A

a) Narrowing between LA –> LV
b)Rheumatic fever (Strep Pyogenes, inc. ASO), A-Fib, SOB
c) Major (polyarthritis, Carditis, Erythema Marginatum, Sydernhams chorea)
Minor ( Fever, Arthrlagia, inc. ESR/CRP)
d)Diastolic Murmur, Rumble w/ open snap.
e) dec. Preload, Balloon Valvotomy

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2
Q

a) Aortic Stenosis?
b) Pt present?
c) Sound?
d) Tx?

A

a) Narrowing b/w aortic valve and systemic
b) Old man with calcification of valve, bicuspid valve, Chest pain, SOB
c) Crescendo-Decresendo Systolic Murmur
d) Valve replace, dec preload

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3
Q

a) Mitral Regurg/Insufficiency?
b) Pt present?
c) Dx?
d) Tx?

A

a) blood reflux from ventricle to atria (inc atrial stretch), due to loose valve
b) papillary/chordae rupture, endocarditis
c) Holosystolic murmur @ apex, and radiates to axilla
d) replace valve

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4
Q

a) Aortic Insufficiency?
b) Pt. Present?
c) Dx?
d) Tx

A

a) Reflux to ventricle causing dilation
b) Floppy valve 2/2 ischemia (MI), infection (endocarditis), Dissection (marfan)
c) Diastolic decrescendo
d) Valve replace

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5
Q

HTN Urgency/Crisis?

A

BP: >180/110 w/o organ damage

Rx w/ PO meds (hydralazine)

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6
Q

HTN Emergency?

A

BP: >180/120 w/ organ damage such as stroke, MI, LOC, N/V, papilledema, inc ICP
Rx: IV meds (labetalol)

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7
Q

Pheochomocytoma?

A

tumor of the adrenal medulla that causes Paroxysmal spells of HTN, sweating, pain,
Dx Urine VMAs and metanephrine
Rx alpha block then beta block then surgery

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8
Q

a) Minimal Change Disease?
b) characteristics?
c) Rx?

A

a) common nephropathy for <18y.o.
b) proteinuria, sudden edema, hypoalbumin and hyperlipid
c) treat with steroids

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9
Q

a) Tamoxifen?
b) use?
c) risk?

A

a) estrogen antagonist at breast, estrogen agonist at endometrium, agonist at osteoclast
b) hormone sensitive breast ca, dec osteoporosis
c) endometrial ca, uterine sarcoma

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10
Q

Essential Tremor Rx

A

Propranolol

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11
Q

a) Pagets Dz of bone (osteitis deformans)?

b) pt. presents?

A

a) inc osteoclasts (inc bone resorption) leads to inc osteoblasts (inc rebuilding)
b) inc head size (hat no longer fits), headaches, hearing loss,

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12
Q

A) Myasthenia Gravis?
b) Pt. present?
C) Rx?

A

a) autoantibodies on nicotinic Ach receptor in motor end plate,
B) “fatigue”, progressive weakness of muscles (chewing, blink, talk, swallow)
C) Anti-cholinesterases (pyridostigmine, neostigmine), Edrophonium (Dx)

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13
Q

McCune Albright

A

Precocious puberty, Cafe au lait spots, polyostic bone dysplasia (multi-bone fractures)

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14
Q

Peutz-Jegher syndrome

A

GI tract polyposis, mucocutaneous pigmentation,

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15
Q

Sturge-Weber

A

Port-wine stain over trigeminal area, MR, seizures, visual impairment

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16
Q

Deferoxamine

A

Iron overdose antidote

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17
Q

Sodium Bicarb

A

ASA and TCA OD

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18
Q

Calcium EDTA

A

Lead chelator

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19
Q

NAC

A

acetominophen tox

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20
Q

epididymis

A

connects efferent ducts from the rear of each testicle to its vas deferens

21
Q

Round ligament (uterus)

A

leaves pelvis via deep inguinal ring and passes through inguinal canal on to the labia majora and mix with the tissue of the mons pubis

22
Q

Cardinal Ligament

A

contains uterine artery and vein

attaches cervix to lateral pelvic wall

23
Q

Broad ligament

A

connects uterus to the walls and floor of the pelvis`

24
Q

4 signs of arthritis

A

Osteophyte form
Joint space narrowing
Subchondral cysts
Subchondral sclerosis

25
Pyloric Stenosis?
- congenital non-bilious projectile vomiting in 4-8 wk old, palpable epigastric mass - Labs hypokalemic alkalosis - Dx with Abdom U/S
26
Hairy cell leukemia
B-cell leukemia Trap + Rx w/ cladribine and bone marrow transplant
27
Kawasaki Dz
>5yo, irritable, high Fever, non-exudative conjunctivitis, mucositis (strawberry tongue), LAD+, Rx w/ High dose aspirin and IVIG Comp - Coronary artery aneurysm
28
SCFE
Obese boy, insdious hip/knee pain, limping PE - loss of abduction, internal rotation of the hip, external rotation of the thigh X-ray - frog leg Tx - pinning to avoid avascular necrosis
29
Carboxyhemoglobulinemia
CO poison, car exhaust | Pt polycythemia, nausea, dizzy, headache
30
theophylline tox
CNS - headache, seizures | Cardiac - aarhythmia
31
Legionella
Gram neg rod CAP in cruise ship, hotel Cx on charcoal agar or urinary antigen Rx w/ macrolides or flouroquinolones
32
- Cyclophosphamide A/E? | - Rescue
- Hemorrhagic cystitis, Bladder CA, sterile | - Mesna, fluids
33
VSD
MC congenital heart defect | Holosystolic murmur >@Left sternal border
34
Wells Score
Determines prob of DVT | -prev DVT, Ca, sedentary, surgery, swollen leg, U/L swelling, pitting edema
35
MGUS
Monoclonal Gammopathy of Undetermined Sig. | -asymptomatic spike of M prot on SPEP, R/O Multiple myeloma, metastatic bone survey, hyperCa w/ normal albumin
36
Bacterial parotitis
dehydrated post-op patients, pain and swelling of jaw
37
Aspergillosis
immunocompetent pt. w/ constitutional symptoms and a "halo-lesion"/"crescent" on CT
38
Thalassemia trait
asymptomatic w/ norm RDW and microcytic anemia, Target cells
39
Ferritin
Stores Iron Low if Iron Def anemia High in Hemochromatosis, sideroblastic anemia
40
Uterine Fibroids
Dysmennorhea, infertility (if submucosal), heavy menses, benign tumors that inc. w/ OCP and preggo and dec with menopause
41
Howell-Jolly Bodies
Nuclear remnant of RBC after a splenectomy pt seen on wright stain
42
Heinz Bodies
Pt. w/ G6P def, RBC w/ Hb precipitated due to oxidize
43
Schistocytes
Fragmented RBC due to mechanical prob
44
Guillian Barre
Teen getting over a viral infection, presents w/ ascending neuropathy/paralysis, and dec DTR
45
measles (rubeola)
fever, non-prod cough, Koplik spots (blue/white spots in mucosa), non-purulent conjunctivit, coryza
46
Chronic Gramulatosous
Dec phagocytosis due to defect in NADPH oxidase, inc inf w/ catalase+ org Dx w/ Nitro-tetrazolium blue
47
Wiskott Aldrich
X-linked rec, young boy w/ eczema, thrombocytopenia and recurrent infxn, low IgM and High IgE/A
48
Chediak Higashi
albino kid w/ recurrent infection, Dx neutropenia and giant lyososomes Tx w/ TMP-SMX and ascorbic acid
49
Hyper IgE (Jobs)
pruritic dermatitis, staph infxn, inc IgE, eosiniphilia and coarse face