USMLE STEP 1

Question 1

Sarcoidosis can cause

Answer 1

high calcium, high phosphate

Question 2

Deficiency o Von-Willebrand factor metalloprotease is seen in which of the following?

Answer 2

thrombotic thrombocytopenia purpura

Question 3

Which one of the following targets RANKL?

Answer 3

denosumab

Question 4

Hypertensive crisis in patients taking MAOI is managed with?

Answer 4

phentolamine

Question 5

Which of the following would have a positive PAS stain?

Answer 5

whipple disease

Question 6

Which one of the following is not a b-cell disorder?

Answer 6

chronic mucocutaneous candidiasis

Question 7

AML is associated with which of the following translocations?

Answer 7

t(15;17)

Question 8

Which of the following is not a part of Beck triad?

Answer 8

pulmonary edema

Question 9

Which of the following is associated with Adult T-cell Leukemia

Answer 9

htlv-1

Question 10

Anti-mitochondrial antibody antibodies are seen in which of the following?

Answer 10

primary biliary cholangitis

Question 11

Which of the following is the trinucleotide for Myonotic Dystrophy?

Answer 11

ctg

Question 12

Tetralogy of Fallot is caused by the abnormal migration of which of the following?

Answer 12

neural crest cells

Question 13

CML is associated with which of the following translocations?

Answer 13

t(9;22)

Question 14

Autoantibodies against anti desmoglein causes?

Answer 14

pemphigus vulgaris

Question 15

Which of the following genetic disorders is associated w chromosome number 17?

Answer 15

neurofibromatosis type 1

Question 16

Triple bubble sign is seen in which of the following conditions?

Answer 16

jejunal atresia

Question 17

Follicular lymphoma is associated with which of the following translocations?

Answer 17

t(14;18)

Question 18

Which of the following causes red man syndrome?

Answer 18

vancomycin

Question 19

Which of the following is not a stop codon?

Answer 19

uua

Question 20

Which of the following is NNRTI?

Answer 20

delavirdine

Question 21

Absent UDP-glucuronosytltransferase is seen in

Answer 21

crigler-najar syndrome

Question 22

Which of the following is CSF?

Answer 22

filgrastim

Question 23

Tularemia is caused by

Answer 23

francisella tularensis

Question 24

Which of the following genetic disorders is associated w chromosome number 18?

Answer 24

Edwards syndrome

Question 25

What is the mode of inheritance of Fragile X syndrome?

Answer 25

x-linked dominant

Question 26

What is the mode of inheritance of Hereditary spherocytosis?

Answer 26

autosomal dominant

Question 27

Which of the following can be used to reverse the action of Director factor Xa inhibitors?

Answer 27

andexanet alfa

Question 28

Gray baby is caused by

Answer 28

chloramphenicol