Uterine disorders Flashcards

1
Q

Mucous retention cyst of endocervical columnar cells occurring when a cleft has been covered by squamous metaplasia

A

Nabothian cyst

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2
Q

Most common lesion of the cervix, assoc w/ intermenstrual or postcoital bleeding

A

Cervical polyps

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3
Q

HPV types involved in Cervical dysplasia

A

16,18,31,33

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4
Q

Current classification system in reporting cervical cytology

A

Bethesda system

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5
Q

Histology of endocervix

A

Columnar glandular cells

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6
Q

Histology of ectocervix

A

Stratified squamous epithelium

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7
Q

Screening recommendation of pap smear

A

3 yrs after onset of sexual activity

Age 21 yrs

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8
Q

Frequency of pap smear in less than 30 y/o

A

annually in conventional method

every 2 yrs in liquid-based method

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9
Q

Intervention for ASCUS pap smear result

A

Colposcopy and biopsy

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10
Q

Test used using iodine for cervical squamous cells to contrast for biopsy

A

Schiller’s test

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11
Q

Test used when T-zone cannot be evaluated

A

Diagnostic conization

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12
Q

Grade 1: very mild-mild dysplasia

A

Low Grade SIL

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13
Q

Grade 2-3: mod to cancer-in-situ (mitotic figures contained in epith)

A

High-grade SIL

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14
Q

Mgt for CIN I

A

Observe, repeat pap smear in 3 mos

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15
Q

CIN 2-3 tx

A
Ablative therapy (cryotx, CO2 laser)
Excisional procedure (LEEP or cold knife conization)
Hysterectomy (if fertility is undesired)
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16
Q

FIGO stage I of cervical Ca

A

confined to the cervix

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17
Q

Most common stage of presentation in cervical cancer

A

Stage III

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18
Q

Mainstay tx for cervical Ca

A

Chemoradiation

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19
Q

FIGO stage II

A

beyond uterus but not to the pelvic wall or to the lower 3rd of the vagina

20
Q

FIGO Stage III

A

Causes hydronephrosis, involves lower third of vagina

21
Q

Most common cause of death in cervical ca

A

Uremia

22
Q

HPV type in genital warts

A

6, 11

23
Q

Only carcinoma that is staged clinically

A

Cervical cancer

24
Q

Vaccine sched for Quadrivalent HPV vaccine

A

0-2-6 mos

25
Q

Most common anatomic mullerian anomaly

A

Category 5: Septate

26
Q

2 Categories of Mullerian anomalies assoc w/ 2nd trimester loss

A

2: Unicornuate
4: Bicornuate

27
Q

Most common type of myoma/ fibroid

A

intramural

28
Q

Most common type of myoma assoc with heavy and prolonged bleeding

A

Submucous myoma

29
Q

What drug is assoc with endometrial polyps

A

tamoxifen

30
Q

When do you order for biopsy in a patient with endometrial polyp instead of simple UTZ only?

A

> 35 y/o with AUB

31
Q

Presence of glands and stroma in abberant location

A

Endometriosis

32
Q

Most common site of endometriosis

A

Ovaries

33
Q

4 etiology of endometriosis

A

Retrograde menstruation
Coelemic metaplasia
Lymphatic / vascular metastasis
Iatrogenic dissemination

34
Q

3 cardinal histo features of endometriosis

A

Ectopic endometrial glands
Ectopic endometrial stroma
Hemorrhage on adjacent tissues (hemosiderin-laden macrophages)

35
Q

Definitive diagnostic procedure for endometriosis

A

Laparoscopy

36
Q

Growth of endometrial glands and stroma into the uterine myometrium to a depth of at least 2.5 mm from basalis layer

A

Adenomyosis

37
Q

Definitive tx for endometriosis

A

TAHBSO

38
Q

Treatment for ovarian endometriosis >2 cm and adnexal enlargements >8cm

A

Surgical (TAHBSO)

39
Q

> 35 y/o, mostly asymptomatic, but in multiparous, with dysmenorrhea and menorrhagia, diffusely enlarged uterus (2-3x bigger)

A

Adenomyosis

40
Q

Diagnostic exam for endometrial hyperplasia

A
Endometrial sampling
(Cytologic aplasia -most impt determinant for premalignant potential)
41
Q

Histo with the highest risk of progression to endometrial cancer

A

Complex with atypia

42
Q

Pathophy of endometrial hyperplasia

A

Chronic unopposed estrogen exposure

43
Q

After tx of endometrial hyperplasia, how many months should the biopsy be repeated?

A

6 mos

44
Q

Most common cause of postmenopausal bleeding

A

Endometrial atrophy

45
Q

Precursor of endometrial carcinoma

A

Atypical complex hyperplasia

46
Q

Most common subtype of endometrial cancer

A

Endometroid

47
Q

Double cervix arising from uterine didelphys with double vagina

A

Bicollis