UTI Flashcards
Most common UTI pathogen?
E. Coli
Describe the non-immune host response to a uti
High osmolality, low pH, flushing mechanism of urine flow
Describe the typical ‘uncomplicated’ UTI patient
Non-pregnant, otherwise healthy female with no anatomical abnormalities. No systemic Sx
Define cystitis
Inflammation of bladder
List a few UTI risk factors
Female, increased sexual activity, urinary retention, catheter insertion, pregnancy, etc
UTI Sx?
Dysuria, cloudy urine, urgency + would have positive urine dipstick test
Compare UTI and pyelonephritis
A more severe UTI. Typically will have pain, nausea, fevee
Should all patients with a UTI get a culture done?
No. Typically only complicated or severe cases
Raised epithelial cells in the culture indicates what?
Bacteria from the skin was in the urine sample. This is why you should try take a mid-stream urine sample
Can the urine dipstick test exclude UTIs?
Yes
Empirical Tx of acute, uncomplicated UTIs?
Trimethoprim, 300mg od for 3 days OR
nitrofurantoin 100mg q6h for 5 days
Why take trimethoprim at night?
Because it in increases the urinary concentration of the drug
Compare men vs women Tx of an uncomplicated UTI
Men = longer duration. Around 7 days
Pyelonephritis Tx?
Same ABs as uncomplicated UTIs, but longer duration - 10-14 days
UTI prophylaxis?
Can be used in patients who get more than 3 UTIs a year, or who self-cathetise.
Use lower dose and frequency to reduce risk of resistance
