UTI Flashcards

1
Q

Give examples of UTIs.

A
  • Pyelonephritis
  • Renal abscess
  • Cystitis
  • Urethritis
  • Prostatitis
  • Epididymo-orchitis
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2
Q

What is the incidence of UTI?

A
  • Common

- Accounts for around 6% of GP consultations

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3
Q

Who is usually affected by UTI?

A
  • F:M 3:1

- Affects 30% of women at some time

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4
Q

What is UTI an important cause of in children?

A

CRF

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5
Q

What is the incidence of pyelonephritis in women?

A

3 per 1,000 women per year

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6
Q

What is the incidence of symptomatic UTI in men?

A

5 per 10,000 men per year

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7
Q

How prevalent is UTI as an HAI?

A

Accounts for around 38% of HAI (the largest contributor)

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8
Q

General factors which make an individual
more susceptible to UTI (or other infection)
include:

A
  • Immunosuppression
  • Steroids
  • Malnutrition
  • Diabetes
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9
Q

What factors may predispose someone to UTI?

A
  • Female sex (short urethra)
  • Sexual intercourse and poor voiding habits
  • Congenital abnormalities e.g. duplex kidney
  • Stasis of urine e.g. due to poor bladder emptying
  • Foreign bodies eg catheters, stones
  • Oestrogen deficiency in postmenopausal women
  • Fistula between bladder & bowel
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10
Q

Why can wiping from front to back after a bowel movement cause UTI?

A

It may force germs into the urethra

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11
Q

What organisms usually cause UTI?

A

Bowel Organisms

  • E. coli
  • Proteus
  • Klebsiella
  • Entercoccus
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12
Q

How can bowel bacteria be transferred to cause UTI?

A
  • Transurethral route
  • Bloodstream
  • Lymphatics
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13
Q

How may bacteria be transferred from the urethra to the bladder?

A
  • Intercourse

- Catheterisation

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14
Q

What events usually occur to result in UTI caused AKI?

A
  • Colonisation
  • Uroepithelium penetration
  • Ascension
  • Pyelonephritis
  • AKI
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15
Q

How can UTI be classified?

A
  • Single episode (90%) vs recurrent

- Complicated vs uncomplicated

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16
Q

What are the clinical features (signs and symptoms) of UTI in children?

A
  • Diarrhoea
  • Excessive crying
  • Fever
  • Nausea and vomiting
  • Not eating
17
Q

What are the clinical features (signs and symptoms) of UTI in adults?

A
  • Flank pain
  • Dysuria (“like passing broken glass”)
  • Cloudy offensive urine
  • Urgency
  • Chills
  • Strangury (desperate to pee but only small/nothing comes out)
  • Confusion (very old people)
18
Q

What are the clinical features of acute pyelonephritis?

A
  • Pyrexia
  • Poor localisation
  • Loin tenderness (renal angle)
  • Signs of dehydration
  • Turbid urine
19
Q

How should UTI be investigated?

A
  • MSSU
  • Urinalysis in ward
  • Microbiology in lab (microscopy and gram staining)
20
Q

What are you looking for in the urinalysis carried out on the ward?

A
  • Blood
  • Leucocytes
  • Protein
  • Nitrites
21
Q

When should culture and sensitivity be carried out on urine samples?

A

Bacteruria >10^5 CFU/ml

22
Q

What should be carried out on children, males or recurrent UTI patients?

A
  • US or IVU may be helpful

- Isotope studies to rule out reflux and scarring

23
Q

What are the principles of UTI management?

A
  • Identify the infecting organism & institute appropriate treatment
  • Identify predisposing factors and treat if possible
24
Q

What is the treatment for UTI?

A
  • Fluids
  • Antibiotics
  • IV antibiotics (for severe infections)
25
What antibiotics can be used in the treatment of UTI?
- Amoxicillin - Cephalosporin - Trimethoprim
26
What can abnormal urinary tracts causes?
Infections and sometimes lead to renal impairment
27
What can cause an abnormal urinary tract?
- Anatomical / neurological abnormalities - Stones - Diabetes
28
How can reflux nephropathy present?
As UTIs in children
29
What causes damage in reflux nephropathy?
Damage is caused by reflux and infection
30
How can reflux nephropathy be investigated?
- Micturating cystogram (radionuclide 99Tc techniques) | - Assess progression by ultrasound scan & biochemistry
31
How is reflux nephropathy treated?
Surgery
32
What advice should be given to those with recurrent infections?
- Fluid intake 2l / day - Void every 2-3 hours by day - Void before bedtime & before and after intercourse
33
When should someone with an indwelling catheter be given antibiotics?
Only is the patient is symptomatic and the catheter should be replaced
34
What is inevitable with indwelling catheters?
Colonisation
35
What type of technique must be carried out with indwelling catheters?
Aseptic
36
What is important to note with bacteruria?
30% will progress to symptomatic illness
37
How can chronic pyelonephritis present?
- Scarring and clubbing - Hypertension/CRF - ?Reflux
38
What can chronic pyelonephritis progress to?
15% progress to renal failure
39
How is chronic pyelonephritis diagnosed?
Radiological diagnosis