Uveitis 1 Flashcards
(41 cards)
How do you grade cell in AC?
0.5+ is 1-5 cell1+ is 6-15 cell 2+ is 16-25 cell3+ is 26-50 cell4+ is >50 cell
The descriptive term “granulomatous” or “non-granulomatous” is applied to chronic, acute, or recurrent uveitis?
chronic
Recurrent uveitis is recurrence of inflammation after how long of a period off medication?
3 months
What is the least common location of uveitis?
Intermediate
What do NSAIDS inhibit?
COX 1 and 2
What do Corticosteroids inhibit?
Arachadonic acid (AA)
What are the IOP complications risk for intravitreal corticosteroid injection?
50% will have IOP rise25% will require glaucoma meds1=2% will require glaucoma surgery
Keratoderma blennorrhagicum and circinate balantitis are found in what disease/condition?
Reactive arthritis
What are two non-infectious etiologies of hypopyon?
Bechet’s and HLA B 27
What are the 3 classifications of JIA and which has more ocular involvement?
- Systemic onset (Still’s disease)2. Polyarticular (more than 4 joints)3. Pauciarticular (less than 4 joints): most ocular inolvement
Pauciarticular JIA is divided into what two types?
Type 1: Girls under age 5Type 2: older boys
What type of IOL should be used in CE/IOL for JIA patients?
acrylic
Is it recommended to use IMT before and after CE for JIA?
yes
Should band keratopathy be treated before CE in JIA patients?
yes
What percentage of Lupus patients have ocular involvement? What percentage of lupus retinopathy?
50%; 3-30% (depending on severity of lupus)
Are men or women more prone to get polyarteritis nodosa
Men
What is the 5 year mortality rate of untreated polyarteritis nodosa?
90%, take it seriously
What is a disease that looks very much like congenital toxoplasmosis on exam but has a specific finding on neuroimaging that help differentiate it.
Congenital lymphocytic choriomeningitis; It has intracerebral calcification concentrated periventricularly vs in congenital toxoplasmosis intracerebral calcifications are diffuse
IL-2, TNF-y, TNF-b, and IL-12 are cytokines produced by what immune cell?
T-h1 cells; these cells also help stimulate plasma cells to secrete IgG3 and IgG1 as well as inhibit T-h2 cells
IL-4, IL-5, IL-10 are cytokines produced by what immune cell?
T-h2 cells; these cells also stimulate plasma cells to produce IgE and IgA; they also inhibit Th-1 cells
How do you distinguish familial juvenile systemic granulomatosis from sarcoid (such as Blau syndrome)?
Family history is key; this is AD and would show up in the family pedigree
What is the main surgical risk currently for developing sympathetic ophthalmia?
vitreoretinal surgery
What stage of VKH do you normally first see the “sun set glow” fundus?
convalescent stage
What is the first line IMT for Behcet disease?
Azathioprine (Anti-metabolite purine analog)
