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Uveitis Flashcards

(45 cards)

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1
Q

Which 6 retinal vasculitis affect venules?

A
  1. Sarcoid
  2. MS
  3. Birdshot
  4. Eales
  5. Bechets
  6. HIV paraviral syndrome
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2
Q

Which 7 retinal vasculitis affect arterioles?

A
  1. SLE
  2. PAN
  3. Necrotizing herpetic retinitis (ARN)
  4. Syphilis
  5. VZV (PORN)
  6. IRVAN
  7. Churg-Strauss syndrome
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3
Q

Which 2 bugs are the cause of late bleb associated endophthalmitis?

A
  1. H flu

2. Strep

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4
Q

Granular CMV retinitis occurs where?

A

Peripherally

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5
Q

What are 3 types of polymorphonuclear leukocytes?

A
  1. Neutrophils - most abundant granulocytes in the blood
  2. Eosinophils - IL-5 most impt mediator
  3. Basophil / mast cell
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6
Q

What are the steps of the immune response arc?

A
  1. Afferent
  2. Processing
  3. Effector
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7
Q

What is type V hypersensitivity?

A

Stimulatory

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8
Q

CAR is seen in what 2 dx?

A
  1. Small cell lung CA

2. Cutaneous melanoma

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9
Q

What is the outer layer of zonal inflm?

A

Fibrotic reparative or granulation tissue infiltrated with NONgranulomatous inflm and plasma cells, presumably secreting specific Antibodies.

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10
Q

What causes an eosinophilic granuloma in the eye?

A

Toxocara granuloma (strong Th2 response)

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11
Q

Which anterior uveitis has moderate severity (red, painful) that has a poor response to steroids?

A

Syphilis

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12
Q

Is vitiritis present in serpiginous choroidopathy?

A

NO

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13
Q

Which 5 Posterior Uveitis with Arteritis and Phlebitis?

A
  1. Toxoplasmosis
  2. Relapsing polychondritis
  3. Wegener granulomatosis
  4. Crohn dx
  5. FROSTED BRANCH ANGITIS
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14
Q

Which cell is the predominant inflm cell in the eye in uveitis?

A

lymphocytes

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15
Q

When are 3 instances when corticosteriods are not indicated?

A
  1. Fuchs heterochromic iridocyclitis
  2. Pars planitis WITHOUT CME
    * 3. peripheral lesions in toxoplasmosis not affecting optic disc or macula**
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16
Q

Recurrent anterior nongraunulomatous uveitis is what?

A

HLA-B27 - DDx

  1. Ankylosing spondylitis
  2. Reiter syndrome (reactive arthritis)
  3. Inflm bowel dz
  4. Psoriatic arthritis
  5. postinfectious, or reactive, arthritis
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17
Q

Pulmonary apical fibrosis and aortitis that is a/w aortic valve insufficiency are complications of what?

A

Ankylosing spondylitis

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18
Q

What is the most common eye lesion in Reiter syndrome?

A

Conjunctivitis - mucopurlent and papillary

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19
Q

What 4 drugs cause uveitis?

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A
  1. Rifabutin
  2. biphosphanates
  3. sulfonamides
  4. diethylcarbamazine (an antifilarial agent)
  5. oral contraceptives
20
Q

What is the tx for Fuch’s heterochromic iridocyclitis?

Study These Flashcards
A

Topical steriods BUT not aggressive tx because inflm persists for decades with good prognosis.

21
Q

HLA-DR15?

Study These Flashcards
A

Multiple sclerosis

22
Q

HLA-DR15 and HLA-DR51?

Study These Flashcards
A

Pars planitis

23
Q

What are the 4 tx steps for Pars planitis?

Study These Flashcards
A
  1. Periocular steriods
  2. Peripheral ablation - PRP / cryo
  3. PPV, EL
  4. Systemic immunomodulatory agents
24
Q

Hep B as a causitive factor with hypertensive retinopathy, cranial nerve palsy, Horners is caused by what?

Study These Flashcards
A

Polyarteritis nodosa

25
Which surgery is the main risk for developing SO?
PPV
26
How do PIC and MFC differ on FA?
Early hyperflurorescence in PIC; both have late staining. (MFC has early blockage)
27
What type of inflm is seen in Bechets?
NONgranulomatous
28
Which 3 d/o do u see stellate KP - diffuse corneal distribution?
1. Fuch's heterochromic iridocyclitis 2. CMV 3. Toxoplasmosis
29
What are the 3 presentation of CMV-R?
1. Classic or fulminant retinitis, typically appearing in the PP 2. Granular or indolent - found more in the periphery 3. Perivascular - similar to frosted branch angitis
30
Migratory arthritis in white males with CN palsys with less than 5% of cases having b/l panuvetis and vasculitis is what?
Whipple dx. Tx with Bactrim
31
A hypopyon occuring in the subretinal or subhyloidal space with hemorrhage in all retinal layers occurs in what?
Aspergillus endophthalmitis
32
What 3 d/o present with a pseudohypopyon?
1. Bechets 2. Leukemia 3. Retinoblastoma
33
CWS with a lesion size over 750um is suggestive of what?
Very early CMV retinitis
34
Cidofovir 2SE are what?
1. Hypotony | 2. Anterior uveitis (immune reconstitution uveitis)
35
HLA-B7/ HLA-DR2?
POHS
36
Cyclosporine / Tacrolimus SE and mechanism?
Nephrotoxicity; T cell signaling
37
Sjogren's causes what type of uveitis?
Intermediate
38
Ig not in tears?
IgD
39
Which drug is the best at treating Bechets?
Chlorambucil
40
When should a steroid sparing agent be used when what level of steriod has been exceeded for a day?
10mg
41
What cause drug induced lupus?
Inflixamab
42
Which uveitis has an initial increase in IOP?
HERPETIC!!
43
Bechcets is HLA?
B51
44
Which dz has life threatening laryngeal inflm?
Relapsing polychondritis
45
Keratoderma blennorrhagicum is what and seen in what?
1. Skin lesions on the palms and soles of feet | 2. REITER's syndrome

Retina / Uveitis (2 decks)

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