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Shelf - Pediatrics > UW > Flashcards

UW Flashcards

1
Q

Prolonged PTT
Normal Plt, BT, PT

Decreased F8 v. F9

A

Hemophilia A and B

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2
Q

Hemarthrosis, intramuscular hematoas, GI/GU bleeding

X-R

A

Hemphilia A and B

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3
Q

Presents at 3-4m with hypoglemia induced seizures, lactic acidosis, hyperuricemia, hyperlipidemia. Thin extremities, doll like face, short stature, protuberant abdomen (HM).

A

Glucose-6-phosphatase deficiency (type 1 - von gierke)

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4
Q

HM, glucocerebrocide accum in macrophages in liver, spleen, marrow = bone pain, cytopenia.

A

Glucocerebrosidase enzyme deficiency - Gaucher

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5
Q

When do you NOT CT a kiddo with head trauma

A

GCS=15
Non-severe mechanism
No vomiting, HA, LoC, signs of fracture

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6
Q

Management of a kiddo with head trauma and
GCS=15 w/any:
Vomiting, HA, brief/questionable LoC, high-risk mechanism, severe mechanism

A

Observe for 4-6hrs

OR

Head CT WITHOUT contrast

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7
Q

Sore throat, dysphagia, odynophagia, pharyngeal/tonsillar erythema

+ cough, rhinorrhea, conjuctivitis, oral ulcers

A

Viral pharyngitis

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8
Q

Sore throat, dysphagia, odynophagia, pharyngealtonsillar erythema

+ edema, palatal petechiae

Next step?

A

Rapid antigen test for strep pharyngitis

MCC: GAS

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9
Q

Rapid antigen strep pharyngitis test is negative, next step?

Rapid antigen strep pharyngitis test is pisitive, next step?

A

If NEGATIVE - throat culture (if negative again, then viral dx)

If POSITIVE - tx with oral amoxicillin or penicillin

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10
Q

Hemophilia A and B are what type of bleeding disorder (clotting defect, platelet aggregation defect, thrombocytopenia)

A

Clotting defect

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11
Q

Increased PTT with hemarthrosis and deep tissue hematomas. Dx?

A

Hemophilia a or B

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12
Q

vWD and bernard soulier syndrome - what type of bleeding disorder? (clotting defect, platelet aggregation defect, thrombocytopenia)

A

Platelet aggregation

Easy or prolonged bleeding, ecchymosis, and petechiaex

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13
Q

Easy or prolonged mucosal bleeding, ecchymosis, petechiae, and decreased platelet count. Bleeding disorder type?

A

Thrombocytopenia

ITP or leukemia

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14
Q

HBsAg
HBeAg
IgM Anti-HBcAg

Which is marker of viral replication

Which is first evidnce of infection

Which is antibodiy to hep B core antigen?

A

Which is marker of viral replication - HBeAg

Which is first evidnce of infection - HBsAg

Which is antibodiy to hep B core antigen?
IgM Anti-HBcAg

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15
Q

What is the clinical feature of iron poisoning present at 2d?

What about during 2-8wk?

A

2d = hepatic necrosis

2-8wk = pyloric stenosis

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16
Q

MCC of otitis externa

Tx

A

Pseudomonas *fluoroquinolones

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17
Q

Vitamin deficiency - diarrhea, dermatitis, dementia, possible death

Associated with UC/nutritional absorption deficiencies and third world countries

A

Pellagra - niacin (B3) deficiency

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18
Q

Vitamin deficiency - cheilosis, glossitis, seborrheic dermatitis, pharyngitis, erythema/edema of mouth

A

Riboflavin (B2)

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19
Q

Vitamin deficiency - irritability, depression, dermatitis, stomatitis, elevated homocysteine concentraiton (atherosclerosis and venous thromboemb RF)

A

Pyridoxine (B6)

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20
Q

Genu varum

A

Rickets - vit D def

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21
Q

Three signs of pancreatic insufficiency in CF

A

Vitamin D deficiency

Vitamin K defiiency - easy bruising

Poor growth

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22
Q

Cat bites (pasteurella) and anaerobic bacteria - ppx tx after bite

A

Amox/clav

23
Q

Preceeding triggers for intussusception

A

Gastroenteritis, meckel’s, polyps, hematomas (HSP - dt bowel wall edema and localized hemorrhage)

24
Q

MCC acute bacterial sinusitis

Tx

A

Strep pneumo or nontypable Haemoph. Infl

Amox-clav

25
Q

MCC of otitis externa

A

Pseudomonas

26
Q

Asian child with sore throat and joint swelling and new onset heart murmur - name the dz, the heart defect, and the abx ppx.

A

Pharyngitis dt GAS –> RF
MS
Penicillin

27
Q

Tx for enterobius vermicularis pinworm

A

Albendazole for the whole house

28
Q

Ectopic/upward facing lens and joint hypermobooloty, pectus excavatum

A

Marfans - fibrillin1

29
Q

Lens downward, pectus deformity, tall stature, arachnodactyly, fair complexion, *thromboembolic events/CVAccident, intellectual disability

A

Homocystinuria (AR - def cystathionine synthase - met. Methionine)

Marfanoid body habitus with the triad of CVA, fair complexion, intellectual disability

30
Q

3-4m with hypoglycemia (seizures), lactic acitosis (glycogen b/u in liver), doll like face, hyperuricemia/lipidemia, HM

A

G6PD (type 1 glycogen storage dz - von Gierke)

31
Q

HM, bone pain, cytopenia due to ___ b/u in macrophages of liver, spleen, marrow

A

Gaucher - glucocerebrosidase enzyme deficiency

32
Q

Hypoketotic hypoglycemia during fasting states

A

MCAD

33
Q

When do you give seizure abortive therapy

A

If >5min (dt increased risk of airway compromise)

34
Q

HA, jaundice, SM, increased MCHC, incrased osmotic fragility test on ACIDIFIED GLYCEROL LYSIS TEST
And ABNORMAL EOSIN-5-MALEIMIDE BINDING TEST

A

Hereditary spherocytosis

35
Q

Define IgA-mediated leukocytoclastic vasculitis and tx

Nml to inc creatinie
Hematuria +/- RBC casts +/- protienuria

Hx: infection

A

HSP

Supportive or if severe, systemic GC

Tetrad: palpable purpura, GI pain, hematuria, arthralgia

36
Q

Posttussive emesis in a child w/o vacinnations after 4y - think?

A

Pertussis

Tx with macrolides - azythro or clarithro

37
Q

Common complication in neonates born <30wk or <3.3lb

Presents with lethargy, hypotonia, high pitched cry, rapidly increasing head circumference, buldging fontanelles)

A

Intraventricular hemorrhage

38
Q

2-6m with HM, protuberant abdomen, hporeflexia, cherry red macula

A

Neimann pick disease (sphingomyelinase)

39
Q

2-6m with hyperreflexia, cherry red macula, loss of motor milestones

A

Tay sachs (beta hexosaminidase A def(

40
Q

Pertussis ppx for household:
<1m
>1m

A

<1m = azithromycin x5d

> 1m = azithromycin x 5d; clarithromycin x 7d; erythromycin x 14d

41
Q

Tx for radial head sublixation

A

Hyperpronate the forearm

OR
Supinate forearm and flex elbow

42
Q

3-10y male with hip pain. Follows viral infection. Pain, deceased ROM, limping. Flexed, abd, ER.

Dx

A

Transient synovitis

43
Q

High pitched cry in newborn. Mom drug user. What drug

A

Heroin

44
Q

G.C testing in what aged

A

all sexually active females < or equal to 24y

45
Q

DKA following a viral illness -what happens to potassium?

A

Decreased total body K due to net renal loss. Serum K may be elevated dyue to acidemia and decreased insulin activity, causing K reditribution into Extracellular space

46
Q 
DKA causes...
K
RAAS
Lipolysis
Volume status
Gluconeogenesis
A 
Loss of K
Increased RAAS
Increased lipolysis
Hypovolemia/osmotic diuresis
Incrased gluconeogenesis dt increased ration of circulating glucagon:insulin
47
Q

Turners are at increased risk for what due to ovarian dysgenesis?

A

Estrogen deficiency –> decrersed inhibition of osteoclast-mediaeted bone resorption –> decreased bone density –>
OSTEOPOROSIS

48
Q

Difference between laryngomalacia and vascualr rings in presentation

A

Laryngomalacia is INSPIRATORY stridor that is worse in supine and better prone.

Vascular rings are BIPHASIC stridor that is better with neck extension

49
Q

Precocious ouberty, cafe au lait spots, multiple bone defects (responsible fo r5% of female precocious puberty)

A

Mccune-albright

50
Q 
LAD 
HSM
anemia/pallor
petechiae/thrombocytopenia
bone pain
marrox bx: >25% blasts
A

ALL

51
Q
  1. Low pitched muscial, pure, or squeaky tone at LLSB
    - Name
    - B9 or pathologic?
  2. High pitched at LUSB
    - Name
    - B9 or pathologic?
A
  1. Stills, b9

2. Pulmonary flow murmur, b9

52
Q

Subcutaneous emphysema secondary to severe coughing… next step in management.

A

CXR to r/o pneumothorax

53
Q

Tx for tourette disorder (>1y)

A

Antipsychotic - risperidone

54
Q

Pericardial effusion can lead to ____ after cardiac surgery?

A

Cardiac tamponade, a result of postpericardiotom syndrome

Shelf - Pediatrics (1 decks)

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