UWorld 2017 Flashcards

1
Q

4 medications + MOAs for open-angle glaucoma

A

Reduce secretion of aqueous humor by ciliary epithelium: nonselective beta blockers (Timolol), carbonic anhydrase inhibitor (Acetazolamide)

Increase outflow of aqueous humor: prostaglandin F2alpha (Latanoprost, Travoprost), cholinomimetics (Pilocarpine, Carbachol)

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2
Q

4 effects of first-generation antihistamines (chlorpheniramine, diphenydramine)

A

Antihistamines
Anticholinergic (impaired accomodation, blurred vision of close objects)
Anti-alpha adrenergic
Antiserotoninergic

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3
Q

Severe HTN changes in eye

A

Endothelial disruption, leakage of plasma into arteriolar wall, fibrinous necrosis
Necrotic Vx bleed in nerve fiber layer: dot/flame-shaped hge

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