UWorld Flashcards

1
Q

What is the classic presenting sign of osteoid osteoma

A

Pain at night that responds well to NSAIDs

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2
Q

What age does stranger anxiety present and when should it resolve by?

A

Presents at 6 months of age, peaks at 9 months of age, should resolve by 2 years of age, anything beyond that is pathologic and hence is termed as separation anxiety disorder

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3
Q

What organisms cause sepsis in Sickle cell disease patients?

A

Strep, H. flu and Nisseria

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4
Q

Of these 3 organisms, which one is the most common and why

A

Strep, due to non type-able strains that are not covered in the vaccine

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5
Q

How can constipation lead to cystitis?

A

rectal distention can obstruct urinary flow, leading to urinary stasis and hence cytitis

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6
Q

What are the 2 neurologic diseases that can cause constipation?

A

Spina bifida and Hirschsprung disease

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7
Q

What are the presenting signs of ALL?

A
  1. Hepatosplenomegaly
  2. Thrombocytopenia
  3. Blast cells on blood smear, on CBC have to be > 25%
  4. Fever, fatigue, lethargy
  5. Bone pain is a common presenting sign since it arises from the bone marrow
  6. Lymphadenopathy
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8
Q

Diagnostic test for ALL

A

Bone marrow biopsy

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9
Q

Parkland formula giving out liquids

A

At 8 and 16 hours

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10
Q

Klumpke palsy causes horners because of involvement of the ___ root?

A

T1

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11
Q

Erb palsy causes breathing difficulties because involvement of the ____ root?

A

C5

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12
Q

3 steps for renal infections caused by reflex

A

Renal US, followed by VCUG to determine reflux and then we do 2, 3 DMSA scan to determine renal scarring

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13
Q

IODM with reduced LV volume

A

Asymmetric septal hypertrophy, this is different from HOCM as children can outgrow this defect

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14
Q

Preauricular tags/pits

A

GU abnormalities and hearing loss, should be followed up with a hearing test and renal US

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15
Q

Presentation of fanconi anemia

A

Initial presentation is thrombocytopenia, neutropenia and then anemia, systemic signs are hypopigmentation, thumb abnormalities and hypogonadism (dont confuse this with triphalangeal thumbs which are a sign of Diamond Blackfan anemia)

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16
Q

Smal left colon syndrome association and first test performed

A

IODM, barium study

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17
Q

Key findings of Legg calves perthes that differentiates it from Transient synovitis

A

Duration longer than 4 weeks, persistent symptoms, limited internal rotation and abduction of the affected hip, positive trendelenburg sign due to atrophy of the proximal thigh muscle

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18
Q

Treatment of Legg calves perthes

A

Conservative management, splinting or bracing, NO IMMEDIATE surgery

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19
Q

Test for posterior uretheral valves to confirm?

A

VCUG

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20
Q

Physical findings of Edwards

A

Prominent occiput, micrognathia, rocker bottom feet, absent palmar crease, CLOSET FISTS WITH OVERLAPPING FINGERS

21
Q

Werdnig Hoffman

A

Symmetric weakness due to degeneration of anterior horn spinal cord neurons, autosomal recessive, death within 1st year of life

22
Q

Dandy Walker syndrome

A

Agenesis of cerebellar vermis, enlargement of 4th venticle

23
Q

Chiari II malformation

A

Herniation of cerebellar vermis through aqueduct leading to aqueduct stenosis and causing non communicating hydrocephalus

24
Q

Congenital strabismus and acquired strabismus treatment

A

acquired; patching of the good eye, congenital; surgery

25
What are low in 17 OH deficiency from of CAH
CORTISOL + SEX Hormones!
26
Cause and treatment of subconjunctival hemorrhage in newborn
Passage through the birth canal, no treatment is needed
27
Interesting lab finding with chlamydia trachomatis pneumonia
Eosinophilia
28
What is the gas pattern in rest of the GI in malrotation vs annular pancreases/duodenal atresia
Normal gas pattern in the rest of the GI in malrotation, no gas in duodenal atression
29
Use of ACEi in neonates
Craniofacial abnormalities
30
Use of warfarin in neonates
Chondrodysplasia and facial abnormalities
31
What vitamin deficiency causes burning feet syndrome
B5
32
What age does TAPVR present with and without obstruction
With obstruction, at birth, without obstruction around 1 - 2 years
33
craniofacial anomalies, cryptorchidism, hypospadias, cardiovascular anomalies, cleft lip/palate, neural tube defects, and/or limb malformations consider _____ exposure in utero
Valproate
34
Complications of rubeola and which one is most common
Pneumonia, meningitis, otits media and SSPE, otitis media is the most common
35
Forshceimmer spots
Rubella, palatal petechiae
36
Mentzer index
MCV/RBC count in millions
37
Medications contraindicated during breast feeding
Lithium, cocaine/heroin/Antineoplastics
38
Pure red cell aplasia is associated with
Thymoma, leukemia, Parvovirus
39
Common cause of death in Duschenne?
Dilated cardiomyopathy
40
Two doses of Varicella vaccine are administered in?
1 and 4 years
41
Cri Du Chat syndrome
High pitched cry, mircocephaly, intellectual disability
42
Most common long term sequelae of bacterial meningitis
Hearing loss
43
How do you do UTI testing in an infant
Cant do clean catch in any one who is diapers, have to do urine cath clean specimen
44
What does plethoric look signify?
Polycythemia most probably
45
When is renal biopsy indicated for peds?
Child less than 10 with nephrotic syndrome who do not respond to steroids
46
How to differentiate between Fanconi anemia and Diamond Blackfan syndrome
Diamond Blackfan is pure red blood cell anemia, platelets and other cells are normal, Fanconi anemia progresses from thrombocytopenia, neutropenia and then anemia
47
What anemia is a misnomer and what is should be called
Aplastic anemia, pancytopenia
48
When not to treat Acute OM
Age > 6 months, with low grade fever, and little to no pain
49
Apgar score for resuscitation
Below 7