UWorld

Question 1

Kcat

Answer 1

Vmax / [E]
unit: s-1

“turnover number”; the number of reactions catalyzed per second per enzyme under saturating conditions (ie, when Vmax is achieved)

Question 2

Michaelis-Menten equation

Answer 2

V0 = Vmax [S] / Km+[S]

Question 3

Henderson-Hasselbach Equation

Answer 3

used for buffer systems to find pH

pH = pKa + log [A-]/[HA]

Question 4

What 2 events could lead to the alteration of chromosome number without losing coding information?

Answer 4

1. end-to-end fusion of chromosomes followed by inactivation of one centromere
2. breakage at centromere (portions then fuse with 2 different chromosomes)