UWorld Flashcards

1
Q

Which type of dementia affects the medial temporal lobe?

A

Alzheimer’s

“Anthony’s grandpa loved eating meat and was lost in time”

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2
Q

What type of dementia affects the frontal and temporal lobes?

A

Frontotemporal

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3
Q

What type of dementia causes ventriculomegaly?

A

Normal pressure hydrocephalus

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4
Q

What type of dementia causes white matter changes on imaging?

A

Vascular

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5
Q

What’s the difference between caput succedaneum vs. cephalohematoma?

A

Caput crosses suture lines

“Caput is not caput”

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6
Q

Which disease causes cafe au lait spots, axillary freckles, Lisch nodules, and peripheral neural sheath tumors?

A

Neurofibromatosis 1

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7
Q

What disease can cause bilateral trigeminal neuralgia?

A

MS

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8
Q

Above what level of the spinal cord must be injured for autonomic dysreflexia to occur?

A

T6

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9
Q

What condition causes severe back pain, fever, and elevated ESR, and requires urgent back MR?

A

Spinal epidural abscess

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10
Q

Could gentamicin cause vertigo and hearing loss?

A

Yes (aminoglycoside toxicity)

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11
Q

How do you treat Bell’s palsy?

A

Glucocorticoids

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12
Q

Which antipsychotic can cause hyperprolactinemia?

A

Risperidone

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13
Q

Does increased prolactin cause decreased dopamine in the tuberoinfundibular pathway?

A

Yes

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14
Q

How does hypothyroidism lead to carpal tunnel?

A

Soft tissue thickening and mucinous infiltration of the nerve tunnel

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15
Q

T/F: Isotretinoin can cause increased ICP/

A

True

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16
Q

What congenital disorder presents with early onset stroke, marfanoid body habitus, light hair and eyes, and vision problems?

A

Homocystinuria

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17
Q

What’s the tx for homocystinuria?

A

B6, folate, and B12 supplementation

18
Q

What can present like Bell’s palsy but also has parotid gland swelling?

A

Sarcoidosis

19
Q

What presents with a young infant with failure to thrive, bilateral cataracts, and jaundice?

A

Galactosemia (galactose-1-phosphate-uridyl transferase deficiency)

20
Q

What can IV drug use lead to with the spine (and would present with lower leg weakness)?

A

Spinal epidural abscess

21
Q

What etiology of increased ICP occurs in AIDS patients with CD4 counts <400 and causes papular skin lesions and is diagnosed with India ink?

A

Cryptococcus neoformans

22
Q

What’s the tx for status epilepticus (seizure lasting 5+ min or 2+ seizures in which the patient does not completely regain consciousness)?

A

Fosphenytoin, Phenytoin, Levetiracetam, Valproic acid

23
Q

What medications can cause acute dystonia?

A

Antipsychotics, particularly haloperidol and fluphenazine

24
Q

What’s the antidote for acute dystonia?

A

Benztropine

25
Which type of dementia would present with executive dysfunction, asymmetric reflexes, and urinary incontinence?
Vascular
26
T/F: childhood breath-holding spells are a variant of vasovagal syncope due to autonomic dysfunction?
True
27
Is Guillain-Barre a neuromuscular junction or peripheral nerve disorder?
Peripheral nerve (autoimmune demyelination)
28
What artery is torn in an epidural hematoma?
MMA | "You need an epidural from the pain of fighting MMA"
29
Which has immediate sx: epidural or subdural hematoma?
Epidural
30
What's the tx for meningioma?
Surgical resection
31
Which level is the peroneal nerve?
L5
32
What meds do you initiate after TIA?
Aspirin & statin
33
What part of the brain is involved in pronator drift?
Pyramidal/corticospinal tract
34
Can a single ring-enhancing lesion be a brain abscess?
Yes
35
What should you check to see if a patient has before giving sumatriptan?
Coronary artery disease (risk of vasospasm)
36
Can copper deficiency cause peripheral neuropathy and skin depigmentation?
Yes
37
What's a rare complication of aortic dissection that can cause anterior cord syndrome?
Anterior spinal cord ischemia
38
What can cause central cord syndrome?
Whiplash injuries in older adults with underlying spondylosis
39
What's a good tx for fibromyalgia?
Amitryptyline
40
Which disease affects ACh receptor antibodies?
Myasthenia Gravis