V300 in Aesthetic Practice: Prescribing, Safety, and Pharmacology Flashcards
(20 cards)
What is the maximum dose of lidocaine with adrenaline in a healthy adult?
7 mg/kg (typically max 500 mg)
What is the legal classification of botulinum toxin in the UK?
Prescription-only medicine (POM)
How many units of Botox are in 0.1 mL if diluted at 100 units in 2.5 mL?
4 units
Which organ is primarily responsible for drug elimination?
Kidneys
What is first-pass metabolism?
Initial metabolism of a drug in the liver after oral administration
What is the mechanism of action of botulinum toxin?
Blocks acetylcholine release at the neuromuscular junction
What drug is used to dissolve hyaluronic acid dermal fillers?
Hyaluronidase
What are early signs of lidocaine toxicity?
Tingling, metallic taste, confusion, seizures
What is the onset of action for Botox?
3–5 days (full effect in 10–14 days)
What is the emergency dose of adrenaline 1:1000 for anaphylaxis in adults?
0.5 mg IM (0.5 mL)
What type of drug is hyaluronidase?
An enzyme that breaks down hyaluronic acid
How often can Botox be safely repeated in the same area?
Every 12 weeks
Which artery is at risk during nasal filler injections?
Dorsal nasal artery
What is the purpose of aspirating before injecting filler?
To avoid intravascular injection
What is the reversal protocol for vascular occlusion?
Stop injecting, massage, apply heat, administer hyaluronidase
What class of drug is chlorphenamine?
Sedating antihistamine (H1 receptor antagonist)
What local anaesthetic is commonly used in fillers?
Lidocaine (typically 0.3–2%)
What is the concentration of adrenaline in 1:1000?
1 mg/mL
Can you prescribe Botox without a face-to-face assessment?
No – it must be face-to-face by a qualified prescriber
What does the Human Medicines Regulations 2012 govern?
The legal framework for prescribing, supplying, and administering medicines in the UK