vaccines

Question 1

live vaccines

Answer 1

MMR
VZ

Question 2

what can pts generally expect in terms of s/e for inactivated and live vaccines?

Answer 2

Many people have no side effects from these vaccines. If you do have side effects, they tend to be mild
and go away in a few days.

Swell, bruising, itch, rash, feeling stiff, sore, or a hard spot / small lump where you had the needle

tired
feel unwell

Fever
Body aches
Sore joints

N/V/diarrhea

https://www.albertahealthservices.ca/assets/info/hp/cdc/if-hp-cdc-ipsm-adolescent-adult-aftercare-104493.pdf

Question 3

MMR-specific vaccine s/e

Answer 3

In addition to the general side effects, the following may happen up to 6 weeks after getting live vaccines:
• Vaccines that protect against MMR – measles-like rash (a blotchy, red rash), rubella-like rash
(rash with red, raised bumps).

Question 4

VA vaccine-specific s/e

Answer 4

In addition to the general side effects, the following may happen up to 6 weeks after getting live vaccines:
• Vaccines that protect against varicella (chickenpox)– varicella-like rash (rash with water-filled blisters). If you get a rash that looks like varicella, keep it covered. If you cannot cover the rash, stay away from anyone who is pregnant, newborn babies, and people with weak immune systems. If you have more than 50 spots, call Health Link at 811.

Question 5

To help with soreness and swelling:

Answer 5

Put a cool, wet cloth over the area where you had the needle.
o Move the arm or leg where you had the needle.
Tylenol

Question 6

To help w/ fever s/e:

Answer 6

Stay hydrated
Tylenol

Question 7

Indications for Provincially Funded Vaccine - Gardasil9

Answer 7

Males and females 17 years up to and including 26 years of age.
• Males and females initiating the HPV vaccine series at 26 years of age who will be 27years of age when they complete the series are eligible for provincially funded vaccine.

Hematopoietic Stem Cell Transplantation (HSCT) Recipients

Solid Organ Transplant (SOT) Candidates and Recipients

Question 8

Gardasil9 3 dose series: recipient, schedule

Answer 8

Individuals 15 years of age and older (3 dose series):
• Dose 1 – day 0
• Dose 2 – 2 months after dose 1
• Dose 3 – 6 months after dose 1

The number of recommended doses in a series is based on the age at administration
of the first dose. In immunocompetent individuals 15 years of age and older who received the first dose between 9 to less than 15 years of age, a two dose schedule
can be used, with the second dose administered at least 6 months after the first dose.

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Question 9

Gardasil9 dose

Answer 9

0.5mL

Question 10

T/F: Gardasil9 contains latex

Answer 10

False. No latex in vaccine or its packaging.

Question 11

Gardasil9 appearance

Answer 11

After agitation, vaccine appears as a white, cloudy liquid.

Question 12

Gardasil9 composition

Answer 12

9-valent HPV vaccine is a non-infectious recombinant vaccine prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58.

Gardasil9 is made from tiny pieces of the HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58). The vaccine helps to train your body to fight them off and stay healthy.

Question 13

How effective is Gardasil 9?

Answer 13

All HPV vaccines have been found to have high efficacy (close to 100%) for prevention of HPV vaccine type-related persistent infection, cervical intraepithelial neoplasia (CIN) 2/3, and adenocarcinoma in situ (AIS) in clinical trials in analyses limited to persons without evidence of infection with the vaccine types at the time of vaccination

HPV vaccines are highly immunogenic. More than 98% of recipients develop an antibody response to HPV types included in the respective vaccines 1 month after completing a full vaccination series.

However, there is no known serologic correlate of immunity and no known minimum titer determined to be protective.
The high efficacy found in the clinical trials to date has precluded identification of a minimum protective antibody titer.

Question 14

What test(s) can be done to check that Gardasil 9 is working?

Answer 14

HPV vaccines are highly immunogenic. More than 98% of recipients develop an antibody response to HPV types included in the respective vaccines 1 month after completing a full vaccination series.

However, there is no known serologic correlate of immunity and no known minimum titer determined to be protective.
The high efficacy found in the clinical trials to date has precluded identification of a minimum protective antibody titer.

Question 15

How long does it take for the body to build an immune response to a vaccine?

Answer 15

The body usually starts to develop an immune response within 2 weeks after immunization with most vaccines. [need a reliable source]

Be sure to complete the vaccine series in order to obtain the intended protection of the vaccine.

Question 16

I just got my last shot of Gardasil. How long does it take for the vaccine to protect me from the HPV strains it covers?

Answer 16

You have taken all three vaccines, so by now you should have long term immunity for the four HPV strains that Gardasil targets.

The body usually starts to develop an immune response within 2 weeks after immunization with most vaccines.

Studies show that you get high levels of protection after one dose of Gardasil. However, studies don’t tell us how long that immunity would last if you did not get the next two vaccines. You need to be vaccinated 3 times over 6 months to make sure you have long term protection.

It is important to remember that if you had one of the four strains of HPV before you got Gardasil, the vaccine will not eliminate that virus from your body. That is why it is important to continue to get regular PAP tests.

Question 17

How long does protection from Gardasil 9 last?

Answer 17

Idk

Question 18

Why should I get Gardasil 9?

Answer 18

HPV vaccines protect against infection with human papillomaviruses (HPV). HPV is a group of more than 200 related viruses, of which more than 40 are spread through direct sexual contact. Among these, two HPV types cause genital warts, and about a dozen HPV types can cause certain types of cancer—cervical, anal, oropharyngeal, penile, vulvar, and vaginal.

Question 19

Gardasil 9 prevents infection with the following nine HPV types:

Answer 19

HPV types 6 and 11, which cause 90% of genital warts (1)

HPV types 16 and 18, two high-risk HPVs that cause about 70% of cervical cancers and an even higher percentage of some of the other HPV-caused cancers (2–4)

HPV types 31, 33, 45, 52, and 58, high-risk HPVs that account for an additional 10% to 20% of cervical cancers

Question 20

Although Gardasil 9 has been approved to be given through age 45 yrs, why is it not recommended for all adults. Why?

Answer 20

HPV vaccination is not recommended for all adults ages 27 through 45 years. Instead, ACIP recommends that clinicians consider discussing with their patients in this age group who were not adequately vaccinated earlier whether HPV vaccination is right for them. HPV vaccination in this age range provides less benefit because more people have already been exposed to the virus.

Question 21

Can Gardasil 9 be administered to pregnant patients?

Answer 21

HPV vaccination should be delayed until after pregnancy, but pregnancy testing is not required before vaccination. There is no evidence that vaccination will affect a pregnancy or harm a fetus.

Question 22

what is pertussis?

Answer 22

Bordetella pertussis (whooping cough)