Vaccines Flashcards
(40 cards)
1
Q
Adenovirus?
A
NON-ATTENUATED, given to military recruits
2
Q
Typhoid? admin?
A
Ty21a, oral
3
Q
Ty21a, oral?
A
Typhoid, live attenuated
4
Q
Polio, Sabin?
A
live attenutated, ORAL
5
Q
Varicella (chickenpox)?
A
live attenuated
6
Q
Smallpox?
A
live attenuated
7
Q
BCG?
A
live attenuated
8
Q
Yellow fever?
A
live attenuated
9
Q
Influenza, intranasal?
A
live attenuated
10
Q
MMR?
A
live attenuated
11
Q
Rotavirus?
A
live attenuated
12
Q
Rabies?
A
killed/inactivated
13
Q
Influenza injection?
A
killed/inactivated
14
Q
polio, salk?
A
killed/inactivated
15
Q
HAV?
A
killed/inactivated
16
Q
typhoid, Vi polycacharide, intramuscular?
A
killed/inactivated
17
Q
HBV(antigen HBsAg)?
A
Subunit
18
Q
HPV (6, 11, 16)?
A
Subunit
19
Q
acellular pertusis (aP)?
A
Subunit
20
Q
N. meningitidis?
A
Subunit
21
Q
S. pneumonia?
A
Subunit
22
Q
H. influenza B?
A
Subunit
23
Q
c. tetani?
A
toxoid
24
Q
C. diphteria?
A
toxoid
25
m/os loses pathogenicity, but retains capacity for transient growth within inoculated host?
live attenuated
26
live attenuated what systems response?
CELLULAR AND HUMORAL
27
live attenuated contraindicated?
in pregnant and immunodeficiency, because can revert to virulent form
28
MMR and varicella can be given to HIV without evidence of immunity if CD4 > 200
.
29
Pathogen is inactivated by heat or chemicals. maintain epitope - important for immune response.?
killed/inactivated
30
killed/inactivated - what response?
ONLY HUMORAL
31
what induces strong, life long response?
live attenuated
32
what is safer than live?
killed/inactivated
33
cons of inactivated?
weaker immune response, booster shoots needed
34
Include only antigens that best stimulaet the immune system?
subunit
35
subunit pros?
lower chance of adverse reactions
36
subunit cons?
expensive, weaker immune response
37
denatured bacterial toxin with intact receptor binding?
toxoid
38
stimulated immune response to make antibodies without potential for causing disease?
toxoid
39
toxoid pros?
protects agains toxins
40
toxoid cons?
antitoxin levels decrease with time, may require booster
