Vaccines Flashcards
(10 cards)
What do beta-lactams target?
synthesis of bacteria cell wall (peptidoglycan)
What do macrolides target?
inhibit prokaryotic ribosomes (translation)
What do quinolines target?
inhibit prokaryotic topoisomerase (gyrase)
Why can’t antibiotics be used to treat viral diseases?
Viruses don’t have cell walls that can be attacked by antibiotics
antibiotics target bacteria, not viruses
What is an attenuated vaccine?
virus is modified so it doesn’t cause disease, lifelong immune response
What is a recombinant vaccine?
The gene that codes for the surface antigen is put into a plasmid in yeast or bacterial cells. Purified protein is used for the vaccine. Lifelong immune response
What is an mRNA vaccine?
gene that codes for surface antigen is put into a plasmid in yeast or bacterial cells. Purified mRNA is used for the vaccine. Easy to make changes in mRNA sequence, boosters required
What is herd immunity?
people in a group/area have achieved immunity against a virus or other infectious agent to make it very difficult for the infection to spread
virus can mutate and people no longer have immunity
What is thimerosal?
vaccine additive that prevents contamination by bacteria and fungi in multi-dose vials, contains ethylmercury
What are 3 factors that impact rates of autism diagnoses?
new screening for children 18-24 months (new diagnosis infrastructure)
different ways of diagnosing varies from state-to-state and country-to-country
access to medical care isn’t the same in rural areas as it is in big cities