Vaccines

Question 1

What is an example of a live attenuated replicating viral vaccine

Answer 1

e.g. measles, mumps and rubella vaccine) or bacteria (e.g. Bacillus Calmette-Guérin vaccine);

Question 2

What is an example of live attenuated non- replicating vaccine

Answer 2

.g. smallpox and mpox vaccine);

Question 3

what vaccines provide a long lasting antibody response?

Answer 3

Live attenuated replicating viral vaccines

Question 4

what vaccines last for months/years and may require a booster

Answer 4

Inactivated or non-replicating vaccines

Question 5

Examples of an inactivated viral vaccine?

Answer 5

(e.g. tick-borne encephalitis vaccine) or bacteria (e.g. meningococcal vaccine);

Question 6

example of an inactivated toxin vaccine

Answer 6

e.g. tetanus and diphtheria vaccines);

Question 7

what type of vaccines should not be routinely administered in pregnancy

Answer 7

live replicating vaccines

Question 8

what vaccines are not recommended in immunocompromised/immunodeficient patients

Answer 8

LIve replicating

Question 9

What vaccines are recommended for individuals with asplenia, splenic dysfunction, or complement disorders (including those taking complement inhibitors)

Answer 9

• Influenza vaccine (inactivated) or influenza vaccine (live);
• Meningococcal groups A with C and W135 and Y vaccine (MenACWY) and meningococcal group B vaccine (rDNA, component, adsorbed) (4CMenB);
• pneumococcal polysaccharide conjugate vaccine (adsorbed) (PCV13 or PCV15) and/or 23-valent pneumococcal polysaccharide vaccine (PPV23). Patients on complement inhibitor therapy with eculizumab are not at increased risk of pneumococcal disease and do not require PPV23 or additional doses of PCV13 or PCV15.