varicella zoster infections Flashcards
(21 cards)
what is varicella
self limiting painful and itchy rash caused by exposure to herpes virus varicella zoster in childhood
mode of transmission
respiratory
aka of varicella
chicken pox
incubation period of varicella
14 days/ A WEEK
progression of the lesion in varicella
malaise->Papules-> clear pink based vesicles-> pustules-> umbilication of pustules-> crust-> clear or leave white scars
presentation of varicella
itching
lesions all over the body
- most on trunk
-least on limbs
dg of varicella
tzanck smear for tzanck cells that show acantholysis
rx of varicella
life attenuated vaccine for proph
aciclovir
famciclovir
rx for severe varicella
valaciclovir
complications of varicella
secondary lesion infection
scarring
hemorrhagic chicken pox leukemia
pneumonitis
dx of varicella
small pox
what is herpes zoster
reactivation of the herpes varicella zoster virus
where does the dormant varicella zoster virus reside in herpes zoster
dorsal (sensory) root ganglion
risk factors for reactivation of herpes zoster
AIDS
old age
hodgkins disease
(reduced immunity)
clinical presentation of herpes zoster
burning pain
erythema
blood filled vesicles unilaterally along a dermatome
progression of the lesion in herpes zoster
vesicles burst in a few days
scabs seperate in 1-3wks
depressed hypopigmented scars remain
when should underlying malignancy or immunocompromosation be suspected in herpes zoster
general chicken pox presentation along with necrotic or hemorrragic segmental lesions
dg of herpes zoster
biopsy
tzanck smear
what does a positive tzanck smear show
multinucleated giant clld and baloon degen of keratinocytes
rx of herpes zoster
systemic aciclovir
late stage: analgesic
complicaions of herpes zoster
secondary bac infec
neuralgic pain
corneal ulcers and scaring
ocular and facial paralysis