Vascular Flashcards

(50 cards)

1
Q

Etiology of peripheral arterial disease

A

Atherosclerosis

Differentials:
Beurger disease - thromboangiitis obliterans
vasculitis - takayasu arteritis, bechet disease
ergot toxicity
vasospasm
Cystic medial degeneration
Popliteal artery aneurysm - showering of emboli
Fibromyalgia dysplasia

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2
Q

Diagnostic criteria of critical limb ischemia

A
  1. rest pain req opioid analgesia
  2. tissue loss - ulcer, gangrene
  3. ABI<0.5, TPI<0.3, Toe pressure<30, Ankle pressure<50
    for more than 2 weeks
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3
Q

Classification for acute limb ischemia

A
Rutherford classification
I: viable
II: threatened (a: marginally, 
image and revasc urgently
b:immediately) - emergency revasc
III: Irreversible, non viable - amputation

Sensory, motor, doppler - arterial and venous

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4
Q

Classification of chronic limb ischemia

A

Fontaine or Rutherford

0 - asymptomatic
1 - mild claud
2- mod claud
3- maj claud
4 - rest pain
5 - minor tissue loss
6 - major tissue loss (more than forefoot)
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5
Q

Investigations for PAD

A

Anatomical

  • arterial duplex (us)
  • CT angiogram
  • lesser used: bone subtraction angiogram, MRA

Perfusion
- ABPI/ TBI

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6
Q

Management of PAD

A

Asymptomatic

  • lifestyle
  • manage various RF (smoking, HTN, DM - HbA1c)
  • statins, single anti pat therapy

Claudicants, non debilitating

  • supervised exercise therapy (30m, 3x/7, for 12w)
  • drugs: naftidrofurul, cilostazol

Claudicants, debilitating; critical limb ischemia:
revascularisation (endoscopic angioplasty/ stenting, subintimal angioplasty vs bypass) - Transatlantic classification

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7
Q

Buerger’s test

A

significant if pallor when raised <20 deg
venous guttering

reactive hyperaemia when foot placed down from bed

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8
Q

What is a positive exercise test

A

fall of ABI >0.2 post exercise

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9
Q

When to repair AAA

A

Asymptomatic: threshold 5.5cm (follow up with u/s) - give statin to slow rate of growth
or >1cm/year or saccular aneurysm (rather than fusiform)
AND patient fit for surgery

Symptomatic: repair ASAP regardless of size - pain or distal embolisation
(optimise for surgery - CVS fx)

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10
Q

Criteria for AAA

A

Normal Aorta: 2-2.5cm
AAA: >3
Aortic diameter>50% than normal
<50%: ectasia

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11
Q

RF AAA
and
RF for rupture

A

smoking
male
family hx
disorders: marfan (fibrillin 1), Ehler danlos syndrome IV (type 3 collagen)
others: HTN, HLD, atherosclerosis, advanced age, hyperhomocysteinemia

RF for rupture:
COPD, smoking, larger initial AAA size, female gender, renal transplant, rate of enlargement

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12
Q

Types of rAAA presentation

A
  1. Classical: hypotension, shock, pain rad to back, pulsatile ab mass
  2. Local contained: radicular symptoms to thigh, groin with GI/urinary obstruction
  3. rupture into IVC (aortocaval fistula): audible ab bruit, venous HTN (swollen cyanotic legs, lower GI bleed, hematuria)
  4. distal embolisation (thrash foot)
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13
Q

Cx of AAA surgery

A

Intra-op: haemorrhage, distal embolisation (thrash), distal limb arterial thrombosis

Early: spinal cord ischemia (paralysis), ARF (oliguria), AMI, CVA, acute sigmoid colon ischemia, pneumonia, ARDS

Late: aortoenteric fistula, graft infection (Dacron graft), false aneurysm formation, sexual dysfunction, renal failure

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14
Q

Endovascular (EVAR) vs open AAA sx repair

A

Short term: endo mortality rate lower, and a/w lower aneurysm relate death

LT (4 y): endo has higher incidence of post op cx and need for re-intervention

endo needs long term follow up with CT angio to check position of stent

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15
Q

Position of SFJ

A

2.5cm inferolateral to pubic tubercle

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16
Q

How to confirm it is saphena varix

A

located at SFJ/ inguinal region, soft, compressible

collapsible when lying down, positive cough impulse

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17
Q

grading of chronic venous insufficiency

A
CEAP classification
0 - normal
1 - telangiectasia (<1mm), reticular veins (1-3mm)
2 - varicose veins (>3mm)
3 - edema 
4 a venous eczema/ hyperpigmentation
4 b atrophie blanche, lipodermatosclerosis
5 - healed ulcer
6 - active venous ulcer
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18
Q

Venous ulcer management

A

first rule out marjolin cancer - biopsy

Conservative: 4 layer compression bandage

  • first ensure ABI >0.8
    1. non stick wound dressing + wool bandage
    2. crepe bandage
    3. blue line bandage (elset)
    4. adhesive bandage (coban)
  • aim ankle pressure ~30mmhg
  • also give: analgesia, antibiotics (if infx), avoid trauma, elevate legs when resting, compression stockings for life after healed

Surgical: split skin graft, venous sx for underlying pathology

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19
Q

Varicose veins management

- cx of surgery

A

Conservative:

  • lifestyle: change job, avoid standing long durations
  • daflon
  • graduated compression stockings

Surgical if: 1. cosmesis, 2. symptomatic, 3. cx

  • high tie with GSV stripping - stab avulsion (CI if DVT)
    (cx: DVT , saphenous nerve injury)
  • US guided injection foam sclerotherapy
    (cx: cutaneous necrosis, hyperpigmentation, telangiectasic matting, thrombophlebitis, allergic reaction, venous
    thromboembolism)
  • endovenous laser/ radiotherapy saphenous vein ablation
    (cx: skin burns, DVT, PE, vein perforation & hematoma, superficial thrombophlebitis)
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20
Q

Anatomical relations of GSV, SSV

A

GSV: passes anterior to medial malleolus, travel with saphenous nerve

SSV: passes posterior to posterior malleolus, travel with sural nerve

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21
Q

Special tests for venous PE

A

tourniquet test, trendelenburg test, perthes test, doppler ultrasound

22
Q

arterial supply of LL

A

aorta > common iliac > int/ext iliac > common femoral

5 br: sup epigastric, sup circumflex art, sup ext pudendal art, deep ext pud art, profunda femoris (3 br: med/lat circumflex fem art, 4 perforating branches)

pop>ant/pos tibial, peroneal arteries

23
Q

Description of dorsalis pedis

A

one third of the way down a line joining the midpoint of the two malleoli to the cleft between the first and second toe located between the extensor halluces longus and extensor digitorium longus

24
Q

location of claudication vs site of dz

  • buttock
  • thigh
  • calf
  • foot
A

buttock/ impotence: stenosis of lower aorta/ common iliac (aortoiliac dz)

thigh: ext iliac, common fem, aortoiliac dz
calf: superficial femoral (femoral-popliteal dz)
foot: tibial peroneal dz

25
Arterial exam - inspection - palpation - special
Inspect: - colour (red, white, purple) - trophic changes: hairless, dry shiny skin, thickened nail - tissue loss: ulcer/ gangrene/ amputation - surrounding skin: cellulitis, nec fas, DM dermopathy - deformities: Charcot Feel: - temp, CRT, bogginess, discharge, inguinal LN - pulses grading Special: beurger Complete: - full neuro LL exam: sensory, motor, peripheral neuropathy - palpate other peri pulses, auscultate for bruit - ab for AAA - ABPI - neck for carotid art stenosis
26
Differentiate between art, venous and neuropathic ulcers
pain: ischemic painful site: distal toes, lat malleolus/ gaiter, medial malleolus/ heel,MT heads size: vary/ large/ - shape: defined/ irregular/ punched edge: punched/ sloping/ clean base: no gran/ gran surrounding skin: pale/ venous signs/ normal temp: cold/ warm/ dry pulses: absent for art sensation/reflex/ vibration: loss in neuropathic bone: in neuro
27
types of amputations
ray, forefoot, lisfranc (trans MT), Chopard (mid-tarsal), syme (thru ankle), BKA, AKA, through knee, hip disarticulation
28
ABPI values | TPI values
ABPI N: >0.9 occlusion: 0.5-0.9 non comp calcified vessel: >1.4 TBI abN: <0.7
29
lab Ix to do for asymptomatic patients to check risk of developing PAD
CRP
30
Best medical therapy for PAD
``` smoking cessation (bupropion) weight reduction LDL < 2.6, high risk<1.8 (statin) Hba1c<7%, podiatrist BP<140/90, <130/80 if DM or renal dz - ACEi SAPT - clopidogrel 75mg > aspirin 100mg ```
31
Indications for amputation
4Ds: dead (ischemic), damaged (trauma), dangerous (gangrene, sepsis, Ca), damn nuisance (infx, neuropathy)
32
Complications of amputation
``` Early: - hematoma, wound infx (gas gangrene) - DVT, PE - phantom limb pain - skin necrosis (poor perfusion of stump > refashioning) - psychological/social coping Late - OM - stump ulceration - stump neuroma - fixed flexion deformity - difficulty mobilising - spurs and osteophytes in underlying bone ```
33
ddx for acute limb ischemia
acute DVT: phegmasia cerulean dolens blue toe syndrome: atheroembolism from AAA purple toe syndrome: cx of wafarin venous insufficiency
34
Causes of acute limb ischemia
``` arterial embolism - cardiac: AF, recent AMI with LV mural thrombus, prosthetic heart valves - non cardiac acute thrombosis - atherosclerosis - hypercoag states: APS, HIT - medium vessel vasculitis arterial trauma dissecting aortic aneurysm ```
35
6Ps of acute limb ischemia
pain, paresthesia, pallor (mottled, duskiness, black), pulseless, paralysis, perishingly cold (heavy limb, intrinsic foot muscles > leg muscles) paresthesia progression: light touch > V >P > deep pain> pressure sense
36
LeRiche Syndrome
occlusion at bifurcation of terminal aorta tetrad: buttock claud + impotence in men + absent femoral and distal pulses + aortoiliac bruits
37
Ls of PAD
Life > Limb > Lifestyle
38
Embolic vs thrombotic cause of acute limb ischemia
source, claud hx, PE, angio EMBOLIC: source present - AF, AMI, no claud hx, pale white leg, contra pulses present, no collaterals on angio, sharp cut off, minimal atherosclerosis THROMBOTIC: no source, claud hx, dusky, contra leg pulses diminished, angio - diffuse atherosclerosis, collaterals well formed, irregular cut off
39
Management of Acute Limb Ischemia
1. Doppler to determine severity via Rutherford Classification 2. Prep for op: op bloods, ECG, CXR, call OT, call vascular surgeon 3. Early coagulation: IV heparin bolus 70unit/kg, then infusion 15unit/kg/hr - maintain PTT 50-75s (2-2.5x normal) 4. improve existing perfusion: dependent position, avoid injuries, heel pressure, extremes of temp, 100%O2, correct hypotension 5. surgical emergency (+- fasiotomy) w on table angiogram (confirm occlusion, determine cause - thrombotic vs embolic, level of occlusion, anatomy) 6. Post op anti coag w heparin and vasodilators if vasospasm 7. mg risk factors (e.g AF)
40
Surgical options for limb salvage
``` Open surgical - embolectomy/ thrombectomy - endarterectomy - bypass grafting - fasciotomy - primary amputation Endovascular - thrombolysis - angioplasty - stenting ```
41
Intra arterial catheter directed thrombolysis - how it works - contraindications
thrombolysis catheter into clot, infuse TPA (alteplase) for 6 hours (in HD) - angioplasty and stent after Contraindications Absolute 􏰀- CVA within past 2 months 􏰀- Active bleeding / recent BGIT past 10 days 􏰀- Intracranial haemorrhage/ vascular brain neoplasm/ neuroSx past 3 months Relative 􏰀- CPR past 10 days 􏰀- Major Sx / trauma past 10 days - 􏰀Uncontrolled HTN
42
Complications of limb salvage
1. Reperfusion injury 2. Rhabdomyolysis > (release K, lactic acid, myoglobin, ) hyperkalemia - arrhythmias tx: hydrate + IV bicarb to alkalinise urine 3. Compartment syndrome (>30mmhg or within 30 of DBP) - 4 compartment fasciotomy
43
Differentials for ischemic rest pain
- Diabetic Neuropathy - Complex Regional Pain Syndrome - Nerve Root Compression - Peripheral Sensory Neuropathy (other than diabetic neuropathy) - Night Cramps - Buerger‟s Disease (thromboangitis obliterans)
44
locations of communicating veins
- SFJunction (GSV into fem vein) - Hunterian perforator: mid-thigh - Dodd‟s perforator: distal thigh - Boyd‟s perforator: knee - Cockett (posterior tibial) perforators: at 5, 10, and 15 cm above the medial malleolus (connects posterior arch vein to posterior tibial vein)
45
Complications of AV access
Mechanical - Stenosis - thrombosis - infx (S aureus) - aneurysm - rupture, bleeding, ulceration Functional - arterial steal syndrome (ischemic pain, neuropathy, ulceration/gangrene) - venous HTN (skin discolouration, hyperpigmentation, ulceration) - CCF (increased venous return) - failure of fistula, graft
46
AV graft - advantages - disadvantages
- large surface area - easy cannulation - short maturation time (3-6w) - easy surgical handling
47
AV fistula - types - advantages - disadvantages - suitability - how to prepare
- Brachio-cephalic, Radio-cephalic, Brachio-Basilic - long term patency, low infx risk, high blood flow rate, least likely to clot, less arterial steal syndrome - long maturation time - presence of vein diameter >4mm (more likely to succeed) - Prep: avoid blood taking, venipuncture, tight clothing
48
AV fistula assessment - rule of 6
at 6 w post creation, diameter of fistula body>6mm depth no more than 0.6cm blood flow rate >600ml/min length of fistula 6cm occlusion of outflow: augmentation of pulse (adequate inflow) raise arm above heart should collapse fistula (adequate drainage) Doppler us
49
Fistula failure definition
fistula that never matured to be useful difficult to cannulate not enough blood flow for successful 2 needle dialysis
50
types of aneurysms
``` Congenital: berry Acquired: - atheromatous (ab, pop, fem) - mycotic (subacute IE) - syphilitic (thoracic) - dissecting (cx: inferior MI, AR) - false - arteriovenous ```