Vasculitis

Question 1

Vasculitis?

Answer 1

Immune mediated vascular damage

Question 2

The two large cell vasculitis are

Answer 2

Giant cell vasculitis

Takayasu arthritis

Question 3

Giant cell arthritis

Answer 3

Affects above 50 years
Affects carotid artery resulting in headache visual disturbance pain while chewing)
Increased ESR over 100

Question 4

Giant cell biopsy shows

Answer 4

Giant cell in elastic laminate

It’s segmental in which it needs to be taken along the section

Question 5

Giant cell arthritis mgt is

Answer 5

Corticosteroids

Question 6

Giant cell arthritis complications

Answer 6

Blindness

Question 7

Takayasu arthritis

Answer 7

Less than 40 years of age
Mgt corticosteroids
Mostly affects aortic branch

Question 8

Medium sized vasculitis

Answer 8

Kawasaki disease
Polyarthritis nedosa
Burgers disease

Question 9

Kawasaki disease

Answer 9

Affects coronary artery

Question 10

Poly arthritis nedosa

Answer 10

Trans mural inflammation

String of bead on angiogram is seen

Question 11

Burgers disease causes clots in

Answer 11

Fingers and toes
20-40 years old age

Question 12

Burgers disease biggest risk factor

Answer 12

Tobacco

Question 13

Wegners granilomatosis

Answer 13

Small cell vasculitis
CANCA positive
Ssx

Saddle nose
Sinusitis
Oral ulcer
Kidney and lung disease

Question 14

Wegners granilomatosis management

Answer 14

Corticosteroids and cyclophosphamide

Question 15

Difference between Wegners granilomatosis and microscopic polyangitis is?

Answer 15

Microscopic polyangitis does not affect arteries in nose

PANCA is positive on WG

In MPA CANCA positive

Question 16

Chrug straw disease

Answer 16

Microscopic polyangitis
skin nose heart damage

Increase eosinophilia

Question 17

Henoch shnokein purpura

Answer 17

Small artery vasculitis
Increase in IGA level
Palapable skin over leg and buttocks
Increase in IGA level is seen

Question 18

What kind of kidney damage is seen in

Henoch shnokein purpura

Answer 18

IGA nephropathy