Venous Thromboembolism

Question 1

What are the 4 main symptoms of venous thromboembolism

Answer 1

Throbbing in calf/thigh in 1 leg when walking or standing
Warm skin around painful area
Swelling in 1 leg
Swollen veins that are hard and sore

Question 2

What can/does unfractioned heparin cause

Answer 2

Thrombocytopenia

Question 3

What 3 things, other than thrombocytopenia, need to be monitored in a patient on unfractioned heparin

Answer 3

Hyperkalaemia
Weight
Renal function

Question 4

What is the mechanism of action of warfarin

Answer 4

Inhibits vitamin k dependant clotting factors

Question 5

What is the mechanism of action of apixaban

Answer 5

Acts via factor 10A to anticoagulate blood

Question 6

What is apixaban reversed by

Answer 6

Andexant Alfa

Question 7

What is the initial treatment for pulmonary embolism

Answer 7

Warfarin and low molecular weight heparin for 5 days [max 3 months]

Question 8

What needs to monitored in a patient taking edoxaban

Answer 8

Renal function
Liver function
Full blood count
Bleeding and bruising